Is body size associated with ovarian cancer in southern Chinese women?

Purpose: To investigate the association between risk of ovarian cancer and body size among southern Chinese women. Methods: A hospital-based case–control study was undertaken in Guangzhou, Guangdong Province, from 2006 to 2008. Participants were 500 incident ovarian cancer patients and 500 controls,...

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Main Authors: Dada, Su, Pasalich, Maria, Binns, Colin, Lee, Andy
Format: Journal Article
Published: Kluwer Academic Publishers 2012
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/29386
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author Dada, Su
Pasalich, Maria
Binns, Colin
Lee, Andy
author_facet Dada, Su
Pasalich, Maria
Binns, Colin
Lee, Andy
author_sort Dada, Su
building Curtin Institutional Repository
collection Online Access
description Purpose: To investigate the association between risk of ovarian cancer and body size among southern Chinese women. Methods: A hospital-based case–control study was undertaken in Guangzhou, Guangdong Province, from 2006 to 2008. Participants were 500 incident ovarian cancer patients and 500 controls, with a mean age of 59 years. Information on adult height and weight was obtained via face-to-face interview using a structured questionnaire. Logistic regression analyses were performed to assess the association between anthropometric factors and the ovarian cancer risk. Results: Compared with women having body weight ≤50 kg and body mass index (BMI) <18.5 kg/m2, the adjusted odds ratios (ORs) of ovarian cancer were 1.84 (95 % confidence interval (CI) 1.34–2.54) and 1.77 (95 % CI 1.04–3.02) in those women who had body weight >55 kg and BMI ≥23 kg/m2, respectively. Significant dose–response relationships were also observed for both weight and BMI (p<0.01). Body height was not significantly associated with ovarian cancer risk. Conclusion: Body weight and BMI were associated with increased risk of ovarian cancer in southern Chinese women.
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spelling curtin-20.500.11937-293862017-09-13T16:08:46Z Is body size associated with ovarian cancer in southern Chinese women? Dada, Su Pasalich, Maria Binns, Colin Lee, Andy height weight ovarian cancer body mass index China Purpose: To investigate the association between risk of ovarian cancer and body size among southern Chinese women. Methods: A hospital-based case–control study was undertaken in Guangzhou, Guangdong Province, from 2006 to 2008. Participants were 500 incident ovarian cancer patients and 500 controls, with a mean age of 59 years. Information on adult height and weight was obtained via face-to-face interview using a structured questionnaire. Logistic regression analyses were performed to assess the association between anthropometric factors and the ovarian cancer risk. Results: Compared with women having body weight ≤50 kg and body mass index (BMI) <18.5 kg/m2, the adjusted odds ratios (ORs) of ovarian cancer were 1.84 (95 % confidence interval (CI) 1.34–2.54) and 1.77 (95 % CI 1.04–3.02) in those women who had body weight >55 kg and BMI ≥23 kg/m2, respectively. Significant dose–response relationships were also observed for both weight and BMI (p<0.01). Body height was not significantly associated with ovarian cancer risk. Conclusion: Body weight and BMI were associated with increased risk of ovarian cancer in southern Chinese women. 2012 Journal Article http://hdl.handle.net/20.500.11937/29386 10.1007/s10552-012-0075-y Kluwer Academic Publishers restricted
spellingShingle height
weight
ovarian cancer
body mass index
China
Dada, Su
Pasalich, Maria
Binns, Colin
Lee, Andy
Is body size associated with ovarian cancer in southern Chinese women?
title Is body size associated with ovarian cancer in southern Chinese women?
title_full Is body size associated with ovarian cancer in southern Chinese women?
title_fullStr Is body size associated with ovarian cancer in southern Chinese women?
title_full_unstemmed Is body size associated with ovarian cancer in southern Chinese women?
title_short Is body size associated with ovarian cancer in southern Chinese women?
title_sort is body size associated with ovarian cancer in southern chinese women?
topic height
weight
ovarian cancer
body mass index
China
url http://hdl.handle.net/20.500.11937/29386