Free ig light chains interact with sphingomyelin and are found on the surface of myeloma plasma cells in an aggregated form

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Free ig light chains interact with sphingomyelin and are found on the surface of myeloma plasma cells in an aggregated form

Free ? L chains (F?LCs) are expressed on the surface of myeloma cells and are being assessed as a therapeutic target for the treatment of multiple myeloma. Despite its clinical potential, the mechanism by which F?LCs interact with membranes remains unresolved. In this study, we show that F?LCs assoc...

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Bibliographic Details
Main Authors:	Hutchinson, A., Ramsland, Paul, Jones, D., Agostino, Mark, Lund, M., Jennings, C., Bockhorni, V., Yuriev, E., Edmundson, A., Raison, R.
Format:	Journal Article
Published:	American Association of Immunologists 2010
Online Access:	http://hdl.handle.net/20.500.11937/29383

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