Coronary CT angiography with single-source and dual-source CT: Comparison of image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated protocols
Background This study is conducted to investigate and compare image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated coronary CT angiography (CCTA) with the use of single-source CT (SSCT) and dual-source CT (DSCT). Methods A total of 209 patients who underwent...
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| Format: | Journal Article |
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Elsevier
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/29273 |
| _version_ | 1848752759079174144 |
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| author | Sabarudin, Akmal Sun, Zhonghua Yusof, A. |
| author_facet | Sabarudin, Akmal Sun, Zhonghua Yusof, A. |
| author_sort | Sabarudin, Akmal |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background This study is conducted to investigate and compare image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated coronary CT angiography (CCTA) with the use of single-source CT (SSCT) and dual-source CT (DSCT). Methods A total of 209 patients who underwent CCTA with suspected coronary artery disease scanned with SSCT (n = 95) and DSCT (n = 114) scanners using prospective ECG-triggered and retrospective ECG-gated protocols were recruited from two institutions. The image was assessed by two experienced observers, while quantitative assessment was performed by measuring the image noise, the signal-to-noise ratio (SNR) and the contrast-to-noise ratio (CNR). Effective dose was calculated using the latest published conversion coefficient factor. Results A total of 2087 out of 2880 coronary artery segments were assessable, with 98.0% classified as of sufficient and 2.0% as of insufficient image quality for clinical diagnosis. There was no significant difference in overall image quality between prospective ECG-triggered and retrospective gated protocols, whether it was performed with DSCT or SSCT scanners. Prospective ECG-triggered protocol was compared in terms of radiation dose calculation between DSCT (6.5 ± 2.9 mSv) and SSCT (6.2 ± 1.0 mSv) scanners and no significant difference was noted (p = 0.99). However, the effective dose was significantly lower with DSCT (18.2 ± 8.3 mSv) than with SSCT (28.3 ± 7.0 mSv) in the retrospective gated protocol. Conclusions Prospective ECG-triggered CCTA reduces radiation dose significantly compared to retrospective ECG-gated CCTA, while maintaining good image quality. |
| first_indexed | 2025-11-14T08:13:43Z |
| format | Journal Article |
| id | curtin-20.500.11937-29273 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:13:43Z |
| publishDate | 2013 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-292732019-02-19T05:35:39Z Coronary CT angiography with single-source and dual-source CT: Comparison of image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated protocols Sabarudin, Akmal Sun, Zhonghua Yusof, A. Retrospective ECG gating Radiation dose Dual-source CT Single-source CT Image quality Prospective ECG triggering Background This study is conducted to investigate and compare image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated coronary CT angiography (CCTA) with the use of single-source CT (SSCT) and dual-source CT (DSCT). Methods A total of 209 patients who underwent CCTA with suspected coronary artery disease scanned with SSCT (n = 95) and DSCT (n = 114) scanners using prospective ECG-triggered and retrospective ECG-gated protocols were recruited from two institutions. The image was assessed by two experienced observers, while quantitative assessment was performed by measuring the image noise, the signal-to-noise ratio (SNR) and the contrast-to-noise ratio (CNR). Effective dose was calculated using the latest published conversion coefficient factor. Results A total of 2087 out of 2880 coronary artery segments were assessable, with 98.0% classified as of sufficient and 2.0% as of insufficient image quality for clinical diagnosis. There was no significant difference in overall image quality between prospective ECG-triggered and retrospective gated protocols, whether it was performed with DSCT or SSCT scanners. Prospective ECG-triggered protocol was compared in terms of radiation dose calculation between DSCT (6.5 ± 2.9 mSv) and SSCT (6.2 ± 1.0 mSv) scanners and no significant difference was noted (p = 0.99). However, the effective dose was significantly lower with DSCT (18.2 ± 8.3 mSv) than with SSCT (28.3 ± 7.0 mSv) in the retrospective gated protocol. Conclusions Prospective ECG-triggered CCTA reduces radiation dose significantly compared to retrospective ECG-gated CCTA, while maintaining good image quality. 2013 Journal Article http://hdl.handle.net/20.500.11937/29273 10.1016/j.ijcard.2012.09.217 Elsevier fulltext |
| spellingShingle | Retrospective ECG gating Radiation dose Dual-source CT Single-source CT Image quality Prospective ECG triggering Sabarudin, Akmal Sun, Zhonghua Yusof, A. Coronary CT angiography with single-source and dual-source CT: Comparison of image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated protocols |
| title | Coronary CT angiography with single-source and dual-source CT: Comparison of image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated protocols |
| title_full | Coronary CT angiography with single-source and dual-source CT: Comparison of image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated protocols |
| title_fullStr | Coronary CT angiography with single-source and dual-source CT: Comparison of image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated protocols |
| title_full_unstemmed | Coronary CT angiography with single-source and dual-source CT: Comparison of image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated protocols |
| title_short | Coronary CT angiography with single-source and dual-source CT: Comparison of image quality and radiation dose between prospective ECG-triggered and retrospective ECG-gated protocols |
| title_sort | coronary ct angiography with single-source and dual-source ct: comparison of image quality and radiation dose between prospective ecg-triggered and retrospective ecg-gated protocols |
| topic | Retrospective ECG gating Radiation dose Dual-source CT Single-source CT Image quality Prospective ECG triggering |
| url | http://hdl.handle.net/20.500.11937/29273 |