The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization

QR Code

The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization

The Duffy antigen/receptor for chemokines (DARC) is an unusual chemokine receptor that binds a large number of inflammatory chemokines of both the CC and CXC families with nanomolar affinity, yet it lacks the ability to signal upon ligand binding. Using bioluminescent resonant energy transfer, we ha...

Full description

Bibliographic Details
Main Authors:	Chakera, Aron, Seeber, R., John, A., Eidne, K., Greaves, D.
Format:	Journal Article
Published:	2008
Online Access:	http://hdl.handle.net/20.500.11937/2923

Similar Items

Characterization of conformational and oligomeric states of proteins
by: Ahmad Fuad, Fazia Adyani
Published: (2018)

Oligomerization and toxicity of Aß fusion proteins
by: Caine, J., et al.
Published: (2011)

Expression, purification, and oligomerization of phosphoprotein of nipah virus
by: Salvamani, Shamala
Published: (2013)

Multiple oligomeric and conformational states of trypanosomatid phosphoglycerate mutases
by: Ahmad Fuad, Fazia Adyani
Published: (2013)

Oligomerization state of the multimerization domain of Nipah virus phosphoprotein
by: Salvamani, Shamala, et al.
Published: (2013)

Trypanosomatid phosphoglycerate mutases have multiple conformational and oligomeric states
by: Blackburn, Elizabeth A., et al.
Published: (2014)

Oligomeric composition of palm olein‐based polyols: the effect of nucleophiles
by: Tuan Ismail, Tuan Noor Maznee, et al.
Published: (2018)

Primary acute dengue and the deletion in chemokine receptor 5 (CCR5D32)
by: Brestovac, Brian, et al.
Published: (2014)

N-terminal domain of prion protein directs its oligomeric association
by: Trevitt, Clare R., et al.
Published: (2014)

Dealuminated ZSM-5 zeolite catalyst for ethylene oligomerization to liquid fuels
by: Saidina Amin, Nor Aishah, et al.
Published: (2002)

Oligomeric and fibrillar amyloid beta 42 induce platelet aggregation partially through GPVI
by: Elaskalani, O., et al.
Published: (2017)

DnaB proteolysis in vivo regulates oligomerization and its localization at oriC in Bacillus subtilis
by: Grainger, William H., et al.
Published: (2010)

Synthesis And Characterization Of Lithium-Modified Mesoporous Catalyst For Solvent-Free Selective Oligomerization Of Glycerol To Diglycerol
by: Ayoub, Muhammad
Published: (2013)

Polysulfone (PSF) Membrane Incorporated With Polyamide-Tethered Polyhedral Oligomeric Silsequioxane (POSS) For Carbon Dioxide Separation
by: Tan, Nur Izzati Fitri Zaquan
Published: (2017)

Chemokine (C-C motif) receptor 7 (CCR7) associates with the tumour immune microenvironment but not progression in invasive breast carcinoma
by: Sonbul, Sultan N., et al.
Published: (2017)

Copy number variation of c-c chemokine ligand 3-like 1 (CCL3L1), c-c chemokine receptor type 5 (CCR5) and CCR2 polymorphisms on the outcomes of antiretroviral therapy among Malaysian HIV patients
by: Mohamad Isa, Irma Izani
Published: (2020)

Oligomeric composition of polyols from fatty acid methyl ester: the effect of ring‐opening reactants of epoxide groups
by: Tuan Ismail, Tuan Noor Maznee, et al.
Published: (2018)

Adsorptive removal of naproxen from water using polyhedral oligomeric silesquioxane (POSS) covalent organic frameworks (COFs)
by: Bala, Suleiman, et al.
Published: (2022)

Structure of the N-terminal oligomerization domain of DnaD reveals a unique tetramerization motif and provides insights into scaffold formation
by: Schneider, S., et al.
Published: (2008)

Pharmacologically antagonizing the CXCR4-CXCL12 chemokine pathway with AMD3100 inhibits sunlight-induced skin cancer
by: Sarchio, Seri Narti Edayu, et al.
Published: (2014)

Investigating cooperativity across adenosine A3 receptor homo- and hetero-oligomers
by: Groenewoud, N.J.A.
Published: (2019)

Role of D1 receptor antagonism in contextual fear learning and memory
by: Heath, Florence
Published: (2015)

The emancipatory discourse in Carol Ann Duffy’s the World’s Wife
by: Abdulkadhim Mhana, Arsetim Zainab, et al.
Published: (2019)

Chemokine receptor expression on dendritic cells is normal in HIV-infected patients with a stable response to ART, but chemokine levels remain elevated
by: Lee, S., et al.
Published: (2011)

Reading Carol Ann Duffy’s “Politics” through unnatural ecopoetics
by: Zainab Abdulkadhim Mhana,, et al.
Published: (2019)

Reading Carol Ann Duffy’s politics through unnatural ecopoetics
by: Abdul Kidhim Mhana, Zainab, et al.
Published: (2019)

A whole blood monokine-based reporter assay provides a sensitive and robust measurement of the antigen-specific T cell response
by: Chakera, Aron, et al.
Published: (2011)

Discovery of AZD-2098 and AZD-1678, two potent and bioavailable CCR4 receptor antagonists
by: Kindon, Nicholas, et al.
Published: (2017)

Sequencing directly from clinical specimens reveals genetic variations in HCMV-encoded chemokine receptor us28 that may influence antibody levels and interactions with human chemokines
by: Waters, Shelley, et al.
Published: (2021)

Design, Synthesis, and Development of Novel Intracellular Allosteric Modulators of CXC Chemokine Receptor 1 and 2
by: Francis, Rhys
Published: (2024)

A mini review on immune role of chemokines and its receptors in snakehead murrel Channa striatus
by: Bhatt, Prasanth, et al.
Published: (2017)

Examining Duffy’s textual space in “Water” and “Cold” through the unnatural ecopoetics concept
by: Abdulkadhim Mhana, Zainab, et al.
Published: (2020)

Examining the mechanism of action of small-molecule negative allosteric modulators of the human chemokine receptor CXCR2
by: Nesheva, Desislava
Published: (2022)

Small molecule-based fluorescent probes as tool compounds for chemokine receptors CXCR4 and ACKR3
by: Dekkers, Sebastian
Published: (2019)

Antigen-specific T cell responses to BK polyomavirus antigens identify functional anti-viral immunity and may help to guide immunosuppression following renal transplantation
by: Chakera, Aron, et al.
Published: (2011)

Single nucleotide polymorphisms in bovine chemokine and toll-like receptors : impacts on disease susceptibility and productivity in dairy cattle
by: Russell, Christopher David
Published: (2013)

Ex-vivo expression of chemokine receptors on cells surrounding cutaneous nerves in patients with HIV-Associated sensory neuropathy
by: Mountford, Jenjira, et al.
Published: (2018)

Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4
by: Manu, K., et al.
Published: (2011)

The enzyme activities of Caf1 and Ccr4 are both required for deadenylation by the human Ccr4-Not nuclease module
by: Maryati, Marayti, et al.
Published: (2015)

Design and elaboration of a tractable tricyclic scaffold to synthesize druglike inhibitors of dipeptidyl peptidase-4 (DPP-4), antagonists of the C–C Chemokine Receptor Type 5 (CCR5), and highly potent and selective phosphoinositol-3 Kinase δ (PI3Kδ) inhibitors
by: Schwehm, Carolin, et al.
Published: (2017)

Cannot write session to /tmp/vufind_sessions/sess_njhb053jdlvuvtsenqec411mja