Attention deficit - hyperactivity disorder in twins: A developmental genetic analysis

Although attention deficit-hyperactivity disorder (ADHD) has a distinct developmental progression and a substantial genetic component, very little is known about the genetic contribution to its development and the question of whether the same genes contribute to ADHD throughout childhood and into ad...

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Main Authors: Hay, David, Bennett, Kellie, Mcstephen, Michael, Rooney, Rosanna, Levy, F.
Format: Journal Article
Published: Taylor & Francis 2004
Online Access:http://hdl.handle.net/20.500.11937/29004
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author Hay, David
Bennett, Kellie
Mcstephen, Michael
Rooney, Rosanna
Levy, F.
author_facet Hay, David
Bennett, Kellie
Mcstephen, Michael
Rooney, Rosanna
Levy, F.
author_sort Hay, David
building Curtin Institutional Repository
collection Online Access
description Although attention deficit-hyperactivity disorder (ADHD) has a distinct developmental progression and a substantial genetic component, very little is known about the genetic contribution to its development and the question of whether the same genes contribute to ADHD throughout childhood and into adolescence. Data from one of the most extensive twin databases, the Australian Twin ADHD Project (ATAP) have shown that ADHD is inherited as a behavioural dimension rather than as a discrete disorder. Behavioural genetic analysis is used in this study with both cross-sectional and longitudinal analyses of inattention and hyperactivity-impulsivity symptoms of ADHD to demonstrate that much of the consistency in behaviour during childhood and early adolescence is due to genetic influences. Genetic analyses help identify environmental influences that impact upon symptoms of inattention and hyperactivity-impulsivity. It is emphasised that the main function of genetic analysis does not lie in simply estimating the heritability of a trait, but rather in contributing to the understanding of developmental progression and environmental factors that may impinge upon this.
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spelling curtin-20.500.11937-290042017-09-13T15:51:39Z Attention deficit - hyperactivity disorder in twins: A developmental genetic analysis Hay, David Bennett, Kellie Mcstephen, Michael Rooney, Rosanna Levy, F. Although attention deficit-hyperactivity disorder (ADHD) has a distinct developmental progression and a substantial genetic component, very little is known about the genetic contribution to its development and the question of whether the same genes contribute to ADHD throughout childhood and into adolescence. Data from one of the most extensive twin databases, the Australian Twin ADHD Project (ATAP) have shown that ADHD is inherited as a behavioural dimension rather than as a discrete disorder. Behavioural genetic analysis is used in this study with both cross-sectional and longitudinal analyses of inattention and hyperactivity-impulsivity symptoms of ADHD to demonstrate that much of the consistency in behaviour during childhood and early adolescence is due to genetic influences. Genetic analyses help identify environmental influences that impact upon symptoms of inattention and hyperactivity-impulsivity. It is emphasised that the main function of genetic analysis does not lie in simply estimating the heritability of a trait, but rather in contributing to the understanding of developmental progression and environmental factors that may impinge upon this. 2004 Journal Article http://hdl.handle.net/20.500.11937/29004 10.1080/00049530410001734829 Taylor & Francis restricted
spellingShingle Hay, David
Bennett, Kellie
Mcstephen, Michael
Rooney, Rosanna
Levy, F.
Attention deficit - hyperactivity disorder in twins: A developmental genetic analysis
title Attention deficit - hyperactivity disorder in twins: A developmental genetic analysis
title_full Attention deficit - hyperactivity disorder in twins: A developmental genetic analysis
title_fullStr Attention deficit - hyperactivity disorder in twins: A developmental genetic analysis
title_full_unstemmed Attention deficit - hyperactivity disorder in twins: A developmental genetic analysis
title_short Attention deficit - hyperactivity disorder in twins: A developmental genetic analysis
title_sort attention deficit - hyperactivity disorder in twins: a developmental genetic analysis
url http://hdl.handle.net/20.500.11937/29004