Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study
The aim of this study is to investigate the hemodynamic effect of the angulations in the left coronary bifurcation on subsequent development of coronary artery disease. Eight 3D left coronary artery models were generated based on the anatomical details and simulated for numerical analysis. The angul...
| Main Authors: | , , |
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| Format: | Conference Paper |
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IEEE Computer Society
2010
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| Online Access: | http://hdl.handle.net/20.500.11937/28788 |
| _version_ | 1848752630018342912 |
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| author | Chachaina, T. Sun, Zhonghua Jewkes, James |
| author2 | Andrew Lewis |
| author_facet | Andrew Lewis Chachaina, T. Sun, Zhonghua Jewkes, James |
| author_sort | Chachaina, T. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The aim of this study is to investigate the hemodynamic effect of the angulations in the left coronary bifurcation on subsequent development of coronary artery disease. Eight 3D left coronary artery models were generated based on the anatomical details and simulated for numerical analysis. The angulations at the left coronary bifurcation were simulated with angles ranging from 120°, 105°, 90°, 75°, 60°, 45°, 30° to 15°. Computational fluid dynamic models were produced for analysis of flow velocity, wall pressure and wall shear stress. Our results showed that wide angled models produced low wall shear stress and high wall pressure at the left coronary bifurcation regions, whereas, flow pattern was more smooth and laminar with narrow angled models than those with wide angle models. Our analysis indicates the flow-field correlation between coronary angulation and development of atherosclerosis. Future studies are required to analyse the realistic coronary models from patients' data with different degree of coronary stenosis. |
| first_indexed | 2025-11-14T08:11:40Z |
| format | Conference Paper |
| id | curtin-20.500.11937-28788 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:11:40Z |
| publishDate | 2010 |
| publisher | IEEE Computer Society |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-287882017-09-13T15:53:33Z Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study Chachaina, T. Sun, Zhonghua Jewkes, James Andrew Lewis Plaque Coronary artery disease Flow velocity Blood flow Angulation Simulation The aim of this study is to investigate the hemodynamic effect of the angulations in the left coronary bifurcation on subsequent development of coronary artery disease. Eight 3D left coronary artery models were generated based on the anatomical details and simulated for numerical analysis. The angulations at the left coronary bifurcation were simulated with angles ranging from 120°, 105°, 90°, 75°, 60°, 45°, 30° to 15°. Computational fluid dynamic models were produced for analysis of flow velocity, wall pressure and wall shear stress. Our results showed that wide angled models produced low wall shear stress and high wall pressure at the left coronary bifurcation regions, whereas, flow pattern was more smooth and laminar with narrow angled models than those with wide angle models. Our analysis indicates the flow-field correlation between coronary angulation and development of atherosclerosis. Future studies are required to analyse the realistic coronary models from patients' data with different degree of coronary stenosis. 2010 Conference Paper http://hdl.handle.net/20.500.11937/28788 10.1109/eScienceW.2010.16 IEEE Computer Society fulltext |
| spellingShingle | Plaque Coronary artery disease Flow velocity Blood flow Angulation Simulation Chachaina, T. Sun, Zhonghua Jewkes, James Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study |
| title | Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study |
| title_full | Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study |
| title_fullStr | Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study |
| title_full_unstemmed | Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study |
| title_short | Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study |
| title_sort | haemodynamic effect of coronary angulations on subsequent development of coronary artery disease: a preliminary study |
| topic | Plaque Coronary artery disease Flow velocity Blood flow Angulation Simulation |
| url | http://hdl.handle.net/20.500.11937/28788 |