Serum Ferritin and Nutritional Status: Insights From an Eating Disorders Clinic Population

Objective: To determine the relationship between serum ferritin and malnutrition in newly assessed patients at a paediatric eating disorders clinic. Design: This was a prospectively assessed clinical cohort study. Setting: Intake assessment clinic of a tertiary eating disorders service for children...

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Main Authors: Nemba, K., Lewis, B., Watson, Hunna, Hoiles, K., Zhang, Guicheng, Forbes, D.
Format: Journal Article
Published: BMJ Publishing Group 2014
Online Access:http://hdl.handle.net/20.500.11937/28637
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author Nemba, K.
Lewis, B.
Watson, Hunna
Hoiles, K.
Zhang, Guicheng
Forbes, D.
author_facet Nemba, K.
Lewis, B.
Watson, Hunna
Hoiles, K.
Zhang, Guicheng
Forbes, D.
author_sort Nemba, K.
building Curtin Institutional Repository
collection Online Access
description Objective: To determine the relationship between serum ferritin and malnutrition in newly assessed patients at a paediatric eating disorders clinic. Design: This was a prospectively assessed clinical cohort study. Setting: Intake assessment clinic of a tertiary eating disorders service for children and adolescents. Methods: Clinical, anthropometric and laboratory features of children and adolescents were systematically measured. The relationship of serum ferritin to other clinical, anthropometric and laboratory measures was determined using linear regression. Results: A total of 121 female patients aged 9.5–17.6 years were included, with body mass index(BMI) z score -5.7 to 1.9 (median -1.3). Using multiple regression, serum ferritin was inversely associated with BMI z score (regression coefficient (ß)=-0.234, 95% CI -0.413 to -0.055) and serum insulin-like growth factor 1 (IGF-1) (ß=-0.476, 95% CI -0.884 to -0.068) and positively associated with alanine aminotransferase (ß=0.357, 95% CI 0.055 to 0.659, controlling for age, pubertal stage and serum iron).Conclusions: In malnourished adolescents with eating disorders increased serum ferritin is associated with lower BMI z score and serum IGF-1.
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spelling curtin-20.500.11937-286372017-09-13T15:17:10Z Serum Ferritin and Nutritional Status: Insights From an Eating Disorders Clinic Population Nemba, K. Lewis, B. Watson, Hunna Hoiles, K. Zhang, Guicheng Forbes, D. Objective: To determine the relationship between serum ferritin and malnutrition in newly assessed patients at a paediatric eating disorders clinic. Design: This was a prospectively assessed clinical cohort study. Setting: Intake assessment clinic of a tertiary eating disorders service for children and adolescents. Methods: Clinical, anthropometric and laboratory features of children and adolescents were systematically measured. The relationship of serum ferritin to other clinical, anthropometric and laboratory measures was determined using linear regression. Results: A total of 121 female patients aged 9.5–17.6 years were included, with body mass index(BMI) z score -5.7 to 1.9 (median -1.3). Using multiple regression, serum ferritin was inversely associated with BMI z score (regression coefficient (ß)=-0.234, 95% CI -0.413 to -0.055) and serum insulin-like growth factor 1 (IGF-1) (ß=-0.476, 95% CI -0.884 to -0.068) and positively associated with alanine aminotransferase (ß=0.357, 95% CI 0.055 to 0.659, controlling for age, pubertal stage and serum iron).Conclusions: In malnourished adolescents with eating disorders increased serum ferritin is associated with lower BMI z score and serum IGF-1. 2014 Journal Article http://hdl.handle.net/20.500.11937/28637 10.1136/archdischild-2012-303272 BMJ Publishing Group restricted
spellingShingle Nemba, K.
Lewis, B.
Watson, Hunna
Hoiles, K.
Zhang, Guicheng
Forbes, D.
Serum Ferritin and Nutritional Status: Insights From an Eating Disorders Clinic Population
title Serum Ferritin and Nutritional Status: Insights From an Eating Disorders Clinic Population
title_full Serum Ferritin and Nutritional Status: Insights From an Eating Disorders Clinic Population
title_fullStr Serum Ferritin and Nutritional Status: Insights From an Eating Disorders Clinic Population
title_full_unstemmed Serum Ferritin and Nutritional Status: Insights From an Eating Disorders Clinic Population
title_short Serum Ferritin and Nutritional Status: Insights From an Eating Disorders Clinic Population
title_sort serum ferritin and nutritional status: insights from an eating disorders clinic population
url http://hdl.handle.net/20.500.11937/28637