To be sure, to be sure: intolerance of uncertainty mediates symptoms of various anxiety disorders and depression
The Intolerance of UncertaintyModel was initially developed as an explanation for worry within the context of generalized anxiety disorder. However, recent research has identified intolerance of uncertainty (IU) as a possible transdiagnostic maintaining factor across the anxiety disorders and depres...
| Main Authors: | , |
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| Format: | Journal Article |
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Elsevier Inc.
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/28236 |
| _version_ | 1848752482081046528 |
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| author | McEvoy, Peter Mahoney, A. |
| author_facet | McEvoy, Peter Mahoney, A. |
| author_sort | McEvoy, Peter |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The Intolerance of UncertaintyModel was initially developed as an explanation for worry within the context of generalized anxiety disorder. However, recent research has identified intolerance of uncertainty (IU) as a possible transdiagnostic maintaining factor across the anxiety disorders and depression. The aim of this study was to determine whether IU mediated the relationship between neuroticismand symptoms related to various anxiety disorders and depression in a treatment-seeking sample (N=328). Consistent with previous research, IU was significantly associated with neuroticism aswell as with symptoms of social phobia, panic disorder and agoraphobia, obsessive-compulsive disorder, generalized anxiety disorder, and depression. Moreover, IU explained unique variance in these symptom measures when controlling for neuroticism. Mediational analyses showed that IU was asignificant partial mediator between neuroticism and all symptom measures, even when controlling for symptoms of other disorders. More specifically, anxiety in anticipation of future uncertainty (prospective anxiety) partially mediated the relationship between neuroticism and symptoms of generalizedanxiety disorder (i.e. worry) and obsessive-compulsive disorder, whereas inaction in the face of uncertainty (inhibitory anxiety) partially mediated the relationship between neuroticism and symptoms of social anxiety, panic disorder and agoraphobia, and depression. Sobel's test demonstrated that all hypothesized meditational pathways were associated with significant indirect effects, although themediation effectwas stronger forworry than other symptoms. Potential implications of these findings for the treatment of anxiety disorders and depression are discussed. |
| first_indexed | 2025-11-14T08:09:19Z |
| format | Journal Article |
| id | curtin-20.500.11937-28236 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:09:19Z |
| publishDate | 2012 |
| publisher | Elsevier Inc. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-282362017-02-28T01:42:33Z To be sure, to be sure: intolerance of uncertainty mediates symptoms of various anxiety disorders and depression McEvoy, Peter Mahoney, A. anxiety transdiagnostic intolerance of uncertainty mediation depression The Intolerance of UncertaintyModel was initially developed as an explanation for worry within the context of generalized anxiety disorder. However, recent research has identified intolerance of uncertainty (IU) as a possible transdiagnostic maintaining factor across the anxiety disorders and depression. The aim of this study was to determine whether IU mediated the relationship between neuroticismand symptoms related to various anxiety disorders and depression in a treatment-seeking sample (N=328). Consistent with previous research, IU was significantly associated with neuroticism aswell as with symptoms of social phobia, panic disorder and agoraphobia, obsessive-compulsive disorder, generalized anxiety disorder, and depression. Moreover, IU explained unique variance in these symptom measures when controlling for neuroticism. Mediational analyses showed that IU was asignificant partial mediator between neuroticism and all symptom measures, even when controlling for symptoms of other disorders. More specifically, anxiety in anticipation of future uncertainty (prospective anxiety) partially mediated the relationship between neuroticism and symptoms of generalizedanxiety disorder (i.e. worry) and obsessive-compulsive disorder, whereas inaction in the face of uncertainty (inhibitory anxiety) partially mediated the relationship between neuroticism and symptoms of social anxiety, panic disorder and agoraphobia, and depression. Sobel's test demonstrated that all hypothesized meditational pathways were associated with significant indirect effects, although themediation effectwas stronger forworry than other symptoms. Potential implications of these findings for the treatment of anxiety disorders and depression are discussed. 2012 Journal Article http://hdl.handle.net/20.500.11937/28236 Elsevier Inc. restricted |
| spellingShingle | anxiety transdiagnostic intolerance of uncertainty mediation depression McEvoy, Peter Mahoney, A. To be sure, to be sure: intolerance of uncertainty mediates symptoms of various anxiety disorders and depression |
| title | To be sure, to be sure: intolerance of uncertainty mediates symptoms of various anxiety disorders and depression |
| title_full | To be sure, to be sure: intolerance of uncertainty mediates symptoms of various anxiety disorders and depression |
| title_fullStr | To be sure, to be sure: intolerance of uncertainty mediates symptoms of various anxiety disorders and depression |
| title_full_unstemmed | To be sure, to be sure: intolerance of uncertainty mediates symptoms of various anxiety disorders and depression |
| title_short | To be sure, to be sure: intolerance of uncertainty mediates symptoms of various anxiety disorders and depression |
| title_sort | to be sure, to be sure: intolerance of uncertainty mediates symptoms of various anxiety disorders and depression |
| topic | anxiety transdiagnostic intolerance of uncertainty mediation depression |
| url | http://hdl.handle.net/20.500.11937/28236 |