Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron)

Should HFE p.C282Y homozygotes with moderately elevated serum ferritin be treated? A randomised controlled trial comparing iron reduction with sham treatment (Mi-iron)

Introduction: HFE p.C282Y homozygosity is the most common cause of hereditary haemochromatosis. There is currently insufficient evidence to assess whether non-specific symptoms or hepatic injury in homozygotes with moderately elevated iron defined as a serum ferritin (SF) of 300-1000 µg/L are relate...

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Bibliographic Details
Main Authors: Ong, S., Dolling, L., Dixon, J., Nicoll, A., Gurrin, L., Wolthuizen, M., Wood, E., Anderson, G., Ramm, G., Allen, K., Olynyk, John, Crawford, D., Kava, J., Ramm, L., Gow, P., Durrant, S., Powell, L., Delatycki, M.
Format: Journal Article
Published: BMJ Publishing Group 2015
Online Access:http://hdl.handle.net/20.500.11937/28122

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