Predictors of health care use among patients with or at high risk of atherothrombotic disease: Two-year follow-up data
Background Atherothrombotic diseases are the leading health problems in the world, both in terms of morbidity and mortality. This study aimed to identify and quantify the predictors of medication, hospital and outpatient service use among patients with or at high risk of atherothrombotic disease. Me...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
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Elsevier Ireland Ltd
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/28105 |
| _version_ | 1848752446210310144 |
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| author | Ademi, Z. Liew, D. Gorelik, A. Bohensky, M. Zomer, E. Hollingsworth, B. Steg, G. Bhatt, D. Reid, Christopher |
| author_facet | Ademi, Z. Liew, D. Gorelik, A. Bohensky, M. Zomer, E. Hollingsworth, B. Steg, G. Bhatt, D. Reid, Christopher |
| author_sort | Ademi, Z. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background Atherothrombotic diseases are the leading health problems in the world, both in terms of morbidity and mortality. This study aimed to identify and quantify the predictors of medication, hospital and outpatient service use among patients with or at high risk of atherothrombotic disease. Methods Two-year follow-up data were analyzed for 2873 Australian participants of the Reduction of Atherothrombosis for Continued Health (REACH) registry. The analysis was performed using generalized linear models with Poisson and Gamma distributions and log link function. Results Participants with hypercholesterolemia, diabetes, hypertension, atrial fibrillation (AF), and history of coronary artery disease (CAD) used more medications (p < 0.0001). The presence of diabetes predicted higher number of outpatient visits (RR = 1.09, 95% CI: 1.07-1.11), as did AF (RR = 1.10, 95% CI: 1.08-1.12). The presence of peripheral artery disease (PAD) regardless of ankle brachial index (ABI) status (abnormal or normal) increased the use of outpatient visits (RR = 1.24, 95% CI: 1.20-1.29 and RR = 1.12, 95% CI: 1.08-1.15), compared to those without PAD. Similarly, the presence of PAD regardless of ABI status increased the risk of vascular interventions, including coronary angioplasty, carotid surgery, amputation affecting lower-limb and peripheral bypass graft (RR = 3.64, 95% CI: 2.01-6.60) (RR = 2.8, 95% CI: 1.6-4.92) compared to patients without PAD. Conclusions The presence of PAD regardless of ABI status predicts a higher number of outpatient visits, non-fatal cardiovascular endpoints and vascular-interventions, while diabetes predicts higher pharmaceutical use and outpatient visits. AF predicts the higher number of outpatient visits and non-fatal cardiovascular events. © 2014 Elsevier Ireland Ltd. |
| first_indexed | 2025-11-14T08:08:45Z |
| format | Journal Article |
| id | curtin-20.500.11937-28105 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:08:45Z |
| publishDate | 2014 |
| publisher | Elsevier Ireland Ltd |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-281052017-09-13T15:15:02Z Predictors of health care use among patients with or at high risk of atherothrombotic disease: Two-year follow-up data Ademi, Z. Liew, D. Gorelik, A. Bohensky, M. Zomer, E. Hollingsworth, B. Steg, G. Bhatt, D. Reid, Christopher Background Atherothrombotic diseases are the leading health problems in the world, both in terms of morbidity and mortality. This study aimed to identify and quantify the predictors of medication, hospital and outpatient service use among patients with or at high risk of atherothrombotic disease. Methods Two-year follow-up data were analyzed for 2873 Australian participants of the Reduction of Atherothrombosis for Continued Health (REACH) registry. The analysis was performed using generalized linear models with Poisson and Gamma distributions and log link function. Results Participants with hypercholesterolemia, diabetes, hypertension, atrial fibrillation (AF), and history of coronary artery disease (CAD) used more medications (p < 0.0001). The presence of diabetes predicted higher number of outpatient visits (RR = 1.09, 95% CI: 1.07-1.11), as did AF (RR = 1.10, 95% CI: 1.08-1.12). The presence of peripheral artery disease (PAD) regardless of ankle brachial index (ABI) status (abnormal or normal) increased the use of outpatient visits (RR = 1.24, 95% CI: 1.20-1.29 and RR = 1.12, 95% CI: 1.08-1.15), compared to those without PAD. Similarly, the presence of PAD regardless of ABI status increased the risk of vascular interventions, including coronary angioplasty, carotid surgery, amputation affecting lower-limb and peripheral bypass graft (RR = 3.64, 95% CI: 2.01-6.60) (RR = 2.8, 95% CI: 1.6-4.92) compared to patients without PAD. Conclusions The presence of PAD regardless of ABI status predicts a higher number of outpatient visits, non-fatal cardiovascular endpoints and vascular-interventions, while diabetes predicts higher pharmaceutical use and outpatient visits. AF predicts the higher number of outpatient visits and non-fatal cardiovascular events. © 2014 Elsevier Ireland Ltd. 2014 Journal Article http://hdl.handle.net/20.500.11937/28105 10.1016/j.ijcard.2014.04.230 Elsevier Ireland Ltd restricted |
| spellingShingle | Ademi, Z. Liew, D. Gorelik, A. Bohensky, M. Zomer, E. Hollingsworth, B. Steg, G. Bhatt, D. Reid, Christopher Predictors of health care use among patients with or at high risk of atherothrombotic disease: Two-year follow-up data |
| title | Predictors of health care use among patients with or at high risk of atherothrombotic disease: Two-year follow-up data |
| title_full | Predictors of health care use among patients with or at high risk of atherothrombotic disease: Two-year follow-up data |
| title_fullStr | Predictors of health care use among patients with or at high risk of atherothrombotic disease: Two-year follow-up data |
| title_full_unstemmed | Predictors of health care use among patients with or at high risk of atherothrombotic disease: Two-year follow-up data |
| title_short | Predictors of health care use among patients with or at high risk of atherothrombotic disease: Two-year follow-up data |
| title_sort | predictors of health care use among patients with or at high risk of atherothrombotic disease: two-year follow-up data |
| url | http://hdl.handle.net/20.500.11937/28105 |