High cyclin D3 expression confers erlotinib resistance in aerodigestive tract cancer

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High cyclin D3 expression confers erlotinib resistance in aerodigestive tract cancer

Background: Prior studies highlighted cyclin D1 as a key biomarker of response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors. This study builds on prior work by examining the roles of cyclin D1, cyclin D3, and cyclin E in mediating erlotinib sensitivity or resistance. Methods...

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Bibliographic Details
Main Authors:	Petty, W., Voelzke, W., Urbanic, J., Varela, V., Waller, L., Swift, C., Graham, Ross, Memoli, V., Dragnev, K.
Format:	Journal Article
Published:	2011
Online Access:	http://hdl.handle.net/20.500.11937/27841

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