Bp44mT: An orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy

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Bp44mT: An orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy

Background and Purpose: Our previous studies demonstrated that a thiosemicarbazone iron chelator (di-2-pyridylketone-4,4-dimethyl-3- thiosemicarbazone; Dp44mT) possesses potent and selective anti-cancer activity but led to cardiotoxicity at non-optimal doses. In this study, we examined the in vivo a...

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Bibliographic Details
Main Authors:	Yu, Yu, Rahmanto, Y., Richardson, D.
Format:	Journal Article
Published:	John Wiley & Sons 2012
Online Access:	http://hdl.handle.net/20.500.11937/27734

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