A Randomized Controlled Trial of an Online Intervention to Improve Gluten-Free Diet Adherence in Celiac Disease
Objectives: To test the effectiveness of an interactive online intervention to improve gluten free diet adherence in adults with celiac disease. Methods: A Randomized controlled trial was conducted. A total of 189 adults with biopsy-confirmed celiac disease were recruited and randomized to receive t...
| Main Authors: | , , |
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| Format: | Journal Article |
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Nature Publishing Group
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/26993 |
| _version_ | 1848752140884901888 |
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| author | Sainsbury, K. Mullan, Barbara Sharpe, L. |
| author_facet | Sainsbury, K. Mullan, Barbara Sharpe, L. |
| author_sort | Sainsbury, K. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Objectives: To test the effectiveness of an interactive online intervention to improve gluten free diet adherence in adults with celiac disease. Methods: A Randomized controlled trial was conducted. A total of 189 adults with biopsy-confirmed celiac disease were recruited and randomized to receive the intervention (n=101) or to a waitlist control condition (n=88). Post-intervention data was available for 70 intervention and 64 waitlist participants. Three month follow-up data was obtained for 46/50 completers from the intervention group. The primary outcome measure was gluten-free diet adherence. Secondary outcomes were gluten-free diet knowledge, quality of life and psychological symptoms. Results: Results were based on intention-to-treat analyses. The intervention group evidenced significantly improved gluten-free diet adherence, and gluten-free diet knowledge following the treatment period relative to the waitlist control group. The change in knowledge did not contribute to the change in adherence. These improvements were maintained at 3-month’ follow-up. Conclusions: The online program was effective in improving adherence and represents a promising resource for individuals with celiac disease who are struggling to achieve or maintain adequate gluten free diet adherence. |
| first_indexed | 2025-11-14T08:03:54Z |
| format | Journal Article |
| id | curtin-20.500.11937-26993 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:03:54Z |
| publishDate | 2013 |
| publisher | Nature Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-269932017-09-13T15:31:14Z A Randomized Controlled Trial of an Online Intervention to Improve Gluten-Free Diet Adherence in Celiac Disease Sainsbury, K. Mullan, Barbara Sharpe, L. Objectives: To test the effectiveness of an interactive online intervention to improve gluten free diet adherence in adults with celiac disease. Methods: A Randomized controlled trial was conducted. A total of 189 adults with biopsy-confirmed celiac disease were recruited and randomized to receive the intervention (n=101) or to a waitlist control condition (n=88). Post-intervention data was available for 70 intervention and 64 waitlist participants. Three month follow-up data was obtained for 46/50 completers from the intervention group. The primary outcome measure was gluten-free diet adherence. Secondary outcomes were gluten-free diet knowledge, quality of life and psychological symptoms. Results: Results were based on intention-to-treat analyses. The intervention group evidenced significantly improved gluten-free diet adherence, and gluten-free diet knowledge following the treatment period relative to the waitlist control group. The change in knowledge did not contribute to the change in adherence. These improvements were maintained at 3-month’ follow-up. Conclusions: The online program was effective in improving adherence and represents a promising resource for individuals with celiac disease who are struggling to achieve or maintain adequate gluten free diet adherence. 2013 Journal Article http://hdl.handle.net/20.500.11937/26993 10.1038/ajg.2013.47 Nature Publishing Group fulltext |
| spellingShingle | Sainsbury, K. Mullan, Barbara Sharpe, L. A Randomized Controlled Trial of an Online Intervention to Improve Gluten-Free Diet Adherence in Celiac Disease |
| title | A Randomized Controlled Trial of an Online Intervention to Improve Gluten-Free Diet Adherence in Celiac Disease |
| title_full | A Randomized Controlled Trial of an Online Intervention to Improve Gluten-Free Diet Adherence in Celiac Disease |
| title_fullStr | A Randomized Controlled Trial of an Online Intervention to Improve Gluten-Free Diet Adherence in Celiac Disease |
| title_full_unstemmed | A Randomized Controlled Trial of an Online Intervention to Improve Gluten-Free Diet Adherence in Celiac Disease |
| title_short | A Randomized Controlled Trial of an Online Intervention to Improve Gluten-Free Diet Adherence in Celiac Disease |
| title_sort | randomized controlled trial of an online intervention to improve gluten-free diet adherence in celiac disease |
| url | http://hdl.handle.net/20.500.11937/26993 |