Ontology-based Knowledge Representation for Protein Data

The advances in information and communication technologies coupled with increased knowledge about genes and proteins have opened new perspectives for study of protein complexes. There is a growing need to integrate the knowledge about various protein complexes for effective disease prevention mechan...

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Main Authors: Chang, Elizabeth, Sidhu, Amandeep, Dillon, Tharam S., Sidhu, B.
Format: Conference Paper
Published: IEEE 2005
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/26904
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author Chang, Elizabeth
Sidhu, Amandeep
Dillon, Tharam S.
Sidhu, B.
author_facet Chang, Elizabeth
Sidhu, Amandeep
Dillon, Tharam S.
Sidhu, B.
author_sort Chang, Elizabeth
building Curtin Institutional Repository
collection Online Access
description The advances in information and communication technologies coupled with increased knowledge about genes and proteins have opened new perspectives for study of protein complexes. There is a growing need to integrate the knowledge about various protein complexes for effective disease prevention mechanisms, individualized medicines and treatments and other accepts of healthcare. In this paper we propose a protein ontology that handles the following computational challenges in the area proteomics and systems biology in general: (1) it provides more accurate interpretations and associations as conclusions are based on data and semantics. (2) It makes it possible to study relationships among proteins, protein folding, behaviour of protein under various environments, and most importantly cellular function of protein. This protein ontology is a unified terminology description integrating various protein database schemas and provides a easier way to predict and understand proteins.
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spelling curtin-20.500.11937-269042017-09-13T15:29:35Z Ontology-based Knowledge Representation for Protein Data Chang, Elizabeth Sidhu, Amandeep Dillon, Tharam S. Sidhu, B. Data Integration Biomedical Systems Protein Ontology Biomedical Ontologies Protein Informatics The advances in information and communication technologies coupled with increased knowledge about genes and proteins have opened new perspectives for study of protein complexes. There is a growing need to integrate the knowledge about various protein complexes for effective disease prevention mechanisms, individualized medicines and treatments and other accepts of healthcare. In this paper we propose a protein ontology that handles the following computational challenges in the area proteomics and systems biology in general: (1) it provides more accurate interpretations and associations as conclusions are based on data and semantics. (2) It makes it possible to study relationships among proteins, protein folding, behaviour of protein under various environments, and most importantly cellular function of protein. This protein ontology is a unified terminology description integrating various protein database schemas and provides a easier way to predict and understand proteins. 2005 Conference Paper http://hdl.handle.net/20.500.11937/26904 10.1109/INDIN.2005.1560433 IEEE fulltext
spellingShingle Data Integration
Biomedical Systems
Protein Ontology
Biomedical Ontologies
Protein Informatics
Chang, Elizabeth
Sidhu, Amandeep
Dillon, Tharam S.
Sidhu, B.
Ontology-based Knowledge Representation for Protein Data
title Ontology-based Knowledge Representation for Protein Data
title_full Ontology-based Knowledge Representation for Protein Data
title_fullStr Ontology-based Knowledge Representation for Protein Data
title_full_unstemmed Ontology-based Knowledge Representation for Protein Data
title_short Ontology-based Knowledge Representation for Protein Data
title_sort ontology-based knowledge representation for protein data
topic Data Integration
Biomedical Systems
Protein Ontology
Biomedical Ontologies
Protein Informatics
url http://hdl.handle.net/20.500.11937/26904