Mitogenomic analyses from ancient DNA

The analysis of ancient DNA is playing an increasingly important role in conservation genetic, phylogenetic and population genetic analyses, as it allows incorporating extinct species into DNA sequence trees and adds time depth to population genetics studies. For many years, these types of DNA analy...

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Main Authors: Paijmans, J., Gilbert, Thomas, Hofreiter, M.
Format: Journal Article
Published: Academic Press 2013
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1055790312002151
http://hdl.handle.net/20.500.11937/26794
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author Paijmans, J.
Gilbert, Thomas
Hofreiter, M.
author_facet Paijmans, J.
Gilbert, Thomas
Hofreiter, M.
author_sort Paijmans, J.
building Curtin Institutional Repository
collection Online Access
description The analysis of ancient DNA is playing an increasingly important role in conservation genetic, phylogenetic and population genetic analyses, as it allows incorporating extinct species into DNA sequence trees and adds time depth to population genetics studies. For many years, these types of DNA analyses (whether using modern or ancient DNA) were largely restricted to the analysis of short fragments of the mitochondrial genome. However, due to many technological advances during the past decade, a growing number of studies have explored the power of complete mitochondrial genome sequences (mitogenomes). Such studies were initially limited to analyses of extant organisms, but developments in both DNA sequencing technologies and general methodological aspects related to working with degraded DNA have resulted in complete mitogenomes becoming increasingly popular for ancient DNA studies as well. To date, at least 124 partially or fully assembled mitogenomes from more than 20 species have been obtained, and, given the rapid progress in sequencing technology, this number is likely to dramatically increase in the future. The increased information content offered by analysing full mitogenomes has yielded major progress with regard to both the phylogenetic positions of extinct species, as well as resolving population genetics questions in both extinct and extant species.
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spelling curtin-20.500.11937-267942017-02-28T01:50:40Z Mitogenomic analyses from ancient DNA Paijmans, J. Gilbert, Thomas Hofreiter, M. Population genetics Phylogeography Mitochondrial DNA Next Generation Sequencing Museum specimens Phylogenetics The analysis of ancient DNA is playing an increasingly important role in conservation genetic, phylogenetic and population genetic analyses, as it allows incorporating extinct species into DNA sequence trees and adds time depth to population genetics studies. For many years, these types of DNA analyses (whether using modern or ancient DNA) were largely restricted to the analysis of short fragments of the mitochondrial genome. However, due to many technological advances during the past decade, a growing number of studies have explored the power of complete mitochondrial genome sequences (mitogenomes). Such studies were initially limited to analyses of extant organisms, but developments in both DNA sequencing technologies and general methodological aspects related to working with degraded DNA have resulted in complete mitogenomes becoming increasingly popular for ancient DNA studies as well. To date, at least 124 partially or fully assembled mitogenomes from more than 20 species have been obtained, and, given the rapid progress in sequencing technology, this number is likely to dramatically increase in the future. The increased information content offered by analysing full mitogenomes has yielded major progress with regard to both the phylogenetic positions of extinct species, as well as resolving population genetics questions in both extinct and extant species. 2013 Journal Article http://hdl.handle.net/20.500.11937/26794 http://www.sciencedirect.com/science/article/pii/S1055790312002151 Academic Press restricted
spellingShingle Population genetics
Phylogeography
Mitochondrial DNA
Next Generation Sequencing
Museum specimens
Phylogenetics
Paijmans, J.
Gilbert, Thomas
Hofreiter, M.
Mitogenomic analyses from ancient DNA
title Mitogenomic analyses from ancient DNA
title_full Mitogenomic analyses from ancient DNA
title_fullStr Mitogenomic analyses from ancient DNA
title_full_unstemmed Mitogenomic analyses from ancient DNA
title_short Mitogenomic analyses from ancient DNA
title_sort mitogenomic analyses from ancient dna
topic Population genetics
Phylogeography
Mitochondrial DNA
Next Generation Sequencing
Museum specimens
Phylogenetics
url http://www.sciencedirect.com/science/article/pii/S1055790312002151
http://hdl.handle.net/20.500.11937/26794