Characterization of the Electrochemical Behavior of Gastrointestinal Fluids Using a Multielectrode Sensor Probe
A characterization of gastrointestinal fluids has been performed by means of an electrochemical sensor that has potential for clinical in vivo and in vitro monitoring applications. The sensor comprised a three-electrode cell with a counter, reference, and four working electrodes, Au, Pt, Ir, and Rh....
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
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IEEE
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/26790 |
| _version_ | 1848752086589636608 |
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| author | Twomey, K. Alvarez de Eulate, E. Marchesi, J. Kolida, S. Gibson, G. Arrigan, Damien Ogurtsov, V. |
| author_facet | Twomey, K. Alvarez de Eulate, E. Marchesi, J. Kolida, S. Gibson, G. Arrigan, Damien Ogurtsov, V. |
| author_sort | Twomey, K. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | A characterization of gastrointestinal fluids has been performed by means of an electrochemical sensor that has potential for clinical in vivo and in vitro monitoring applications. The sensor comprised a three-electrode cell with a counter, reference, and four working electrodes, Au, Pt, Ir, and Rh. Cyclic voltammetry was used to obtain chemical information from faecal water (in vitro) and gut model (in vivo) fluids. Stable voltammetric responses were obtained for both fluids at these noble metal workingelectrodes. The responses differed in shape that demonstrated the discrimination capability and the potential for practical use as a tool for gastrointestinal fluid investigation. The analysis of the stabilityprofiles in faecal water over a 14-h duration has indicated a possible adsorptionmechanism with the formation of a biolayer on the sensor surface. The stability in gut model fluids over a 42-h durationhas demonstrated a more stable profile, but themechanisms involved are more complicated to determine. |
| first_indexed | 2025-11-14T08:03:02Z |
| format | Journal Article |
| id | curtin-20.500.11937-26790 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T08:03:02Z |
| publishDate | 2011 |
| publisher | IEEE |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-267902017-09-13T15:51:39Z Characterization of the Electrochemical Behavior of Gastrointestinal Fluids Using a Multielectrode Sensor Probe Twomey, K. Alvarez de Eulate, E. Marchesi, J. Kolida, S. Gibson, G. Arrigan, Damien Ogurtsov, V. electrode voltammetry Electrochemical gastrointestinal fluids A characterization of gastrointestinal fluids has been performed by means of an electrochemical sensor that has potential for clinical in vivo and in vitro monitoring applications. The sensor comprised a three-electrode cell with a counter, reference, and four working electrodes, Au, Pt, Ir, and Rh. Cyclic voltammetry was used to obtain chemical information from faecal water (in vitro) and gut model (in vivo) fluids. Stable voltammetric responses were obtained for both fluids at these noble metal workingelectrodes. The responses differed in shape that demonstrated the discrimination capability and the potential for practical use as a tool for gastrointestinal fluid investigation. The analysis of the stabilityprofiles in faecal water over a 14-h duration has indicated a possible adsorptionmechanism with the formation of a biolayer on the sensor surface. The stability in gut model fluids over a 42-h durationhas demonstrated a more stable profile, but themechanisms involved are more complicated to determine. 2011 Journal Article http://hdl.handle.net/20.500.11937/26790 10.1109/TBME.2011.2158543 IEEE fulltext |
| spellingShingle | electrode voltammetry Electrochemical gastrointestinal fluids Twomey, K. Alvarez de Eulate, E. Marchesi, J. Kolida, S. Gibson, G. Arrigan, Damien Ogurtsov, V. Characterization of the Electrochemical Behavior of Gastrointestinal Fluids Using a Multielectrode Sensor Probe |
| title | Characterization of the Electrochemical Behavior of Gastrointestinal Fluids Using a Multielectrode Sensor Probe |
| title_full | Characterization of the Electrochemical Behavior of Gastrointestinal Fluids Using a Multielectrode Sensor Probe |
| title_fullStr | Characterization of the Electrochemical Behavior of Gastrointestinal Fluids Using a Multielectrode Sensor Probe |
| title_full_unstemmed | Characterization of the Electrochemical Behavior of Gastrointestinal Fluids Using a Multielectrode Sensor Probe |
| title_short | Characterization of the Electrochemical Behavior of Gastrointestinal Fluids Using a Multielectrode Sensor Probe |
| title_sort | characterization of the electrochemical behavior of gastrointestinal fluids using a multielectrode sensor probe |
| topic | electrode voltammetry Electrochemical gastrointestinal fluids |
| url | http://hdl.handle.net/20.500.11937/26790 |