Reactive oxygen and nitrogen species generation, antioxidant defenses, and β-cell function: a critical role for amino acids

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Reactive oxygen and nitrogen species generation, antioxidant defenses, and β-cell function: a critical role for amino acids

Growing evidence indicates that the regulation of intracellular reactive oxygen species (ROS) and reactive nitrogen species (RNS) levels is essential for maintaining normal β-cell glucose responsiveness. While long-term exposure to high glucose induces oxidative stress in β cells, conflicting result...

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Bibliographic Details
Main Authors:	Newsholme, Philip, Rebelato, E., Abdulkader, F., Krause, M., Carpinelli, A., Curi, R.
Format:	Journal Article
Published:	BioScientifica Ltd. 2012
Subjects:	amino acids insulin pancreatic glucose b-cell antioxidant defences
Online Access:	http://hdl.handle.net/20.500.11937/26446

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