A novel route to copper(ii) detection using 'click' chemistry-induced aggregation of gold nanoparticles

A simple colorimetric method for the detection of copper ions in water is described. This method is based on the 'click' copper(i)-catalyzed azide-alkyne cycloaddition reaction and its use in promoting the aggregation of azide-tagged gold nanoparticles by a dialkyne cross-linker is describ...

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Bibliographic Details
Main Authors: Hua, C., Zhang, W., De Almeida, S., Ciampi, Simone, Gloria, D., Liu, G., Harper, J., Gooding, J.
Format: Journal Article
Published: Royal Society of Chemistry 2012
Online Access:http://hdl.handle.net/20.500.11937/26098
Description
Summary:A simple colorimetric method for the detection of copper ions in water is described. This method is based on the 'click' copper(i)-catalyzed azide-alkyne cycloaddition reaction and its use in promoting the aggregation of azide-tagged gold nanoparticles by a dialkyne cross-linker is described. Nanoparticle cross-linking, evidenced as a colour change, is used for the detection of copper ions. The lowest detected concentration by the naked eye was 1.8 µM, with the response linear with log(concentration) between 1.8-200 µM. The selectivity relative to other potentially interfering ions was evaluated.