Use of fungal transformants expressing ß-glucuronidase activity to detect and measure hyphal biomass in infected plant tissues

Strains of the tomato pathogen Cladosporium fulvum and the Brassica pathogen Leptosphaeria maculans constitutively expressing Beta-glucuronidase were produced by cotransformation of a hygromycin-encoding vector pAN7-1 and a GUS encoding vector pNOM102. Their Beta-glucuronidase activity was used to d...

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Main Authors: Oliver, Richard, Farman, M., Jones, J., Hammond-Kosack, K.
Format: Journal Article
Published: 1993
Online Access:http://hdl.handle.net/20.500.11937/25976
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author Oliver, Richard
Farman, M.
Jones, J.
Hammond-Kosack, K.
author_facet Oliver, Richard
Farman, M.
Jones, J.
Hammond-Kosack, K.
author_sort Oliver, Richard
building Curtin Institutional Repository
collection Online Access
description Strains of the tomato pathogen Cladosporium fulvum and the Brassica pathogen Leptosphaeria maculans constitutively expressing Beta-glucuronidase were produced by cotransformation of a hygromycin-encoding vector pAN7-1 and a GUS encoding vector pNOM102. Their Beta-glucuronidase activity was used to detect histochemically the presence of fungal hyphae in host plant tissue. In addition, the Beta-glucuronidase activity of C. fulvum was used to quantify fungal biomass in the cotyledons of near-isogenic lines of tomato containing either no Cf resistance gene, or Cf-3, Cf-5, or Cf-9 resistance genes. Beta-Glucuronidase activity was significantly reduced in incompatible interactions on Cf3, Cf5, and Cf9 plants as compared to the compatible interaction on Cf0. Histochemical staining could also differentiate these interactions. These results demonstrate that the production of Beta-glucuronidase-expressing strains of fungi provides a facile means to detect infection and quantify biomass. Applications of this technique are discussed.
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spelling curtin-20.500.11937-259762017-09-13T15:55:37Z Use of fungal transformants expressing ß-glucuronidase activity to detect and measure hyphal biomass in infected plant tissues Oliver, Richard Farman, M. Jones, J. Hammond-Kosack, K. Strains of the tomato pathogen Cladosporium fulvum and the Brassica pathogen Leptosphaeria maculans constitutively expressing Beta-glucuronidase were produced by cotransformation of a hygromycin-encoding vector pAN7-1 and a GUS encoding vector pNOM102. Their Beta-glucuronidase activity was used to detect histochemically the presence of fungal hyphae in host plant tissue. In addition, the Beta-glucuronidase activity of C. fulvum was used to quantify fungal biomass in the cotyledons of near-isogenic lines of tomato containing either no Cf resistance gene, or Cf-3, Cf-5, or Cf-9 resistance genes. Beta-Glucuronidase activity was significantly reduced in incompatible interactions on Cf3, Cf5, and Cf9 plants as compared to the compatible interaction on Cf0. Histochemical staining could also differentiate these interactions. These results demonstrate that the production of Beta-glucuronidase-expressing strains of fungi provides a facile means to detect infection and quantify biomass. Applications of this technique are discussed. 1993 Journal Article http://hdl.handle.net/20.500.11937/25976 10.1094/MPMI-6-521 restricted
spellingShingle Oliver, Richard
Farman, M.
Jones, J.
Hammond-Kosack, K.
Use of fungal transformants expressing ß-glucuronidase activity to detect and measure hyphal biomass in infected plant tissues
title Use of fungal transformants expressing ß-glucuronidase activity to detect and measure hyphal biomass in infected plant tissues
title_full Use of fungal transformants expressing ß-glucuronidase activity to detect and measure hyphal biomass in infected plant tissues
title_fullStr Use of fungal transformants expressing ß-glucuronidase activity to detect and measure hyphal biomass in infected plant tissues
title_full_unstemmed Use of fungal transformants expressing ß-glucuronidase activity to detect and measure hyphal biomass in infected plant tissues
title_short Use of fungal transformants expressing ß-glucuronidase activity to detect and measure hyphal biomass in infected plant tissues
title_sort use of fungal transformants expressing ß-glucuronidase activity to detect and measure hyphal biomass in infected plant tissues
url http://hdl.handle.net/20.500.11937/25976