Selection biases in observational studies affect associations between 'moderate' alcohol consumption and mortality
Selection biases may lead to systematic overestimate of protective effects from ‘moderate’ alcohol consumption. Overall, most sources of selection bias favor low-volume drinkers in relation to non-drinkers. Studies that attempt to address these types of bias generally find attenuated or non-signific...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
| Published: |
Wiley-Blackwell Publishing Ltd.
2016
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| Online Access: | http://hdl.handle.net/20.500.11937/25824 |
| _version_ | 1848751814886817792 |
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| author | Naimi, T. Stockwell, Tim Zhao, J. Xuan, Z. Dangardt, F. Saitz, R. Liang, W. Chikritzhs, T. |
| author_facet | Naimi, T. Stockwell, Tim Zhao, J. Xuan, Z. Dangardt, F. Saitz, R. Liang, W. Chikritzhs, T. |
| author_sort | Naimi, T. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Selection biases may lead to systematic overestimate of protective effects from ‘moderate’ alcohol consumption. Overall, most sources of selection bias favor low-volume drinkers in relation to non-drinkers. Studies that attempt to address these types of bias generally find attenuated or non-significant relationships between low-volume alcohol consumption and cardiovascular disease, which is the major source of possible protective effects on mortality from low-volume consumption. Furthermore, observed mortality effects among established low-volume consumers are of limited relevance to health-related decisions about whether to initiate consumption or to continue drinking purposefully into old age. Short of randomized trials with mortality end-points, there are a number of approaches that can minimize selection bias involving low-volume alcohol consumption. |
| first_indexed | 2025-11-14T07:58:43Z |
| format | Journal Article |
| id | curtin-20.500.11937-25824 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:58:43Z |
| publishDate | 2016 |
| publisher | Wiley-Blackwell Publishing Ltd. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-258242017-09-13T15:35:33Z Selection biases in observational studies affect associations between 'moderate' alcohol consumption and mortality Naimi, T. Stockwell, Tim Zhao, J. Xuan, Z. Dangardt, F. Saitz, R. Liang, W. Chikritzhs, T. Selection biases may lead to systematic overestimate of protective effects from ‘moderate’ alcohol consumption. Overall, most sources of selection bias favor low-volume drinkers in relation to non-drinkers. Studies that attempt to address these types of bias generally find attenuated or non-significant relationships between low-volume alcohol consumption and cardiovascular disease, which is the major source of possible protective effects on mortality from low-volume consumption. Furthermore, observed mortality effects among established low-volume consumers are of limited relevance to health-related decisions about whether to initiate consumption or to continue drinking purposefully into old age. Short of randomized trials with mortality end-points, there are a number of approaches that can minimize selection bias involving low-volume alcohol consumption. 2016 Journal Article http://hdl.handle.net/20.500.11937/25824 10.1111/add.13451 Wiley-Blackwell Publishing Ltd. restricted |
| spellingShingle | Naimi, T. Stockwell, Tim Zhao, J. Xuan, Z. Dangardt, F. Saitz, R. Liang, W. Chikritzhs, T. Selection biases in observational studies affect associations between 'moderate' alcohol consumption and mortality |
| title | Selection biases in observational studies affect associations between 'moderate' alcohol consumption and mortality |
| title_full | Selection biases in observational studies affect associations between 'moderate' alcohol consumption and mortality |
| title_fullStr | Selection biases in observational studies affect associations between 'moderate' alcohol consumption and mortality |
| title_full_unstemmed | Selection biases in observational studies affect associations between 'moderate' alcohol consumption and mortality |
| title_short | Selection biases in observational studies affect associations between 'moderate' alcohol consumption and mortality |
| title_sort | selection biases in observational studies affect associations between 'moderate' alcohol consumption and mortality |
| url | http://hdl.handle.net/20.500.11937/25824 |