A retrospective study investigating the rate of HER2 discordance between primary breast carcinoma and locoregional or metastatic disease

QR Code

A retrospective study investigating the rate of HER2 discordance between primary breast carcinoma and locoregional or metastatic disease

Background: Overall survival of HER2 positive metastatic breast cancer patients has been significantly improved with inclusion of trastuzumab to chemotherapy. Several studies have demonstrated discordant HER2 status in the primary and metastatic tumour. However, rates of discordance vary considerabl...

Full description

Bibliographic Details
Main Authors:	Chan, Arlene, Morey, A., Brown, B., Hastrich, D., Willsher, P., Ingram, D.
Format:	Journal Article
Published:	2012
Online Access:	http://hdl.handle.net/20.500.11937/25823

Similar Items

HER2 positive metastatic breast cancer: What happens after first line failure?
by: Chan, Arlene
Published: (2016)

Capecitabine and vinorelbine in metastatic breast cancer
by: Chan, Arlene, et al.
Published: (2009)

TILs in metastatic breast cancer—no surprises, but more questions
by: Chan, Arlene
Published: (2017)

Bevacizumab in combination with taxanes for the first-line treatment of metastatic breast cancer
by: Chan, Arlene, et al.
Published: (2010)

Phase II, open-label trial of lapatinib and vinorelbine in women with previously treated HER2-positive metastatic breast cancer
by: Chan, Arlene, et al.
Published: (2014)

Neratinib in HER-2-positive breast cancer: Results to date and clinical usefulness
by: Chan, Arlene
Published: (2016)

Biomarker results from the AVADO phase 3 trial of first-line bevacizumab plus docetaxel for HER2-negative metastatic breast cancer
by: Miles, D., et al.
Published: (2013)

Prognostic factors associated with locoregional recurrence in colon cancer
by: Liska, David, et al.
Published: (2014)

Preoperative taxane-based chemotherapy in a standardized protocol for locally advanced breast cancer
by: Chan, Arlene, et al.
Published: (2012)

Phase II study of a triple combination of oral vinorelbine, capecitabine and trastuzumab as first-line treatment in HER2-positive metastatic breast cancer
by: Chan, Arlene, et al.
Published: (2013)

Neratinib after trastuzumab in patients with HER2-positive breast cancer - Author's reply
by: Chan, Arlene, et al.
Published: (2016)

AVEREL: A Randomised Phase 111 Trial Evaluating Bevacizumab in Combination With Docetaxel and Trastuzumab As First-Line Therapy for HER-2Positive Locally Recurrent/Metastatic Breast Cancer
by: Gianni, L., et al.
Published: (2013)

Impact of breast cancer grade discordance on prediction of outcome
by: Rakha, Emad A., et al.
Published: (2018)

Final Results of the Randomized Phase II NorCap-CA223 Trial Comparing First-Line All-Oral Versus Taxane-Based Chemotherapy for HER2-Negative Metastatic Breast Cancer
by: Cinieri, S., et al.
Published: (2017)

Diagnostic pitfalls of metastatic lobular breast carcinoma to the endometrium in a patient on long-standing tamoxifen therapy
by: Chew, Pong Keong, et al.
Published: (2022)

Prevalence and management of HER2/neu-positive early breast cancer in a single institution following availability of adjuvant trastuzumab
by: Chan, Arlene, et al.
Published: (2012)

RESILIENCE: Phase III Randomized, Double-Blind Trial Comparing Sorafenib With Capecitabine Versus Placebo With Capecitabine in Locally Advanced or Metastatic HER2-Negative Breast Cancer
by: Baselga, J., et al.
Published: (2017)

Metastatic thyroid carcinoma presenting with spinal cord compression.
by: Hassan, H. A., et al.
Published: (2010)

Cediranib in combination with fulvestrant in hormone-sensitive metastatic breast cancer: a randomized Phase 11 study
by: Hyams, D., et al.
Published: (2013)

Adjuvant trastuzumab in HER2-positive breast cancer.
by: Slamon, D., et al.
Published: (2011)

Phase 1b dose-finding study of motesanib with docetaxel or paclitaxel in patients with metastatic breast cancer
by: De Boer, R., et al.
Published: (2012)

BCL-2, HER1, HER2, HER3 and HER4 expression in primary colorectal adenocarcinoma
by: Ahmad Zubir, Nurul Mahirah
Published: (2017)

Randomized phase II placebo-controlled study to evaluate the efficacy of topical pure emu oil for joint pain related to adjuvant aromatase inhibitor use in postmenopausal women with early breast cancer: JUST (Joints Under Study)
by: Chan, Arlene, et al.
Published: (2017)

Survival after metastasectomy for metastatic urothelial carcinoma: a systematic review and meta-analysis
by: Patel, Vaibhav, et al.
Published: (2017)

Expression of HER4 isoforms and HER4 localisation in HER2 negative breast cancer cell lines
by: Ali, Nursyazana Aqilah
Published: (2021)

Evaluating the expression of HMGCR in HER2 negative and HER2 positive breast cancer
by: Drahman, Rosmaizan
Published: (2022)

The role of HER family signalling in breast cancer
by: Kuruppu, Anchala
Published: (2016)

Pigment epithelium-derived factor and menopause in metastatic breast cancer
by: Brook, Naomi Louise
Published: (2022)

Cytoplasmic and nuclear HER4 expression in HER2 negative breast cancer cell lines
by: Siti Norasikin Mohd Nafi,, et al.
Published: (2022)

Fine needle aspiration cytology of metastatic renal cell carcinoma - a case report
by: Wan Muhaizan Wan Mustaffa,, et al.
Published: (2006)

Biological characterisation of HER2 amplified breast cancer
by: Barros, Fabrício Félix Tabuada
Published: (2013)

Evaluation of fatty liver in breast cancer patients and its metastatic potential
by: Ahmad, Nor Hayati
Published: (2021)

The study of relationship between cancer markers and age of patient in primary and metastatic paraffinized breast cancer tissue / Nur Azimah Osman
by: Osman, Nur Azimah
Published: (2009)

On discordance test for the wrapped normal data
by: Adzhar Rambli,, et al.
Published: (2012)

A rare case of scrotal basal cell carcinoma in the presence of metastatic squamous cell carcinoma of the external auditory meatus and its management strategy
by: Tan, Guan Hee, et al.
Published: (2017)

Role of novel therapeutic agents in modulating invadopodia formation in metastatic breast cancer
by: Siti Nor Aini Harun,, et al.
Published: (2020)

A rare case of monostotic spinal fibrous dysplasia mimicking solitary metastatic lesion of thyroid carcinoma
by: Sharifudin, Mohd Ariff, et al.
Published: (2016)

Lymphovascular invasion in breast carcinoma
by: Norhisham, Nur Fatiha
Published: (2015)

Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer
by: Dent, R., et al.
Published: (2013)

Discordance between pain and inflammation in rheumatoid arthritis
by: McWilliams, Daniel F.
Published: (2018)

Cannot write session to /tmp/vufind_sessions/sess_88529n0bfs44tu3nij3k4vvnvj