Targeting PDK1 in cancer

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Targeting PDK1 in cancer

Abnormal activation of phosphoinositide 3-kinase (PI3K) signalling is very common in cancer, leading to deregulation of several intracellular processes normally controlled by this enzyme, including cell survival, growth, proliferation and migration. Mutations in the gene encoding the tumour suppress...

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Bibliographic Details
Main Authors:	Raimondi, C., Falasca, Marco
Format:	Journal Article
Published:	2011
Online Access:	http://hdl.handle.net/20.500.11937/25718

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