Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing

A novel nonenzymatic glucose sensor was developed based on well-dispersed gold nanoparticles, which were in situ grown under direction of protein on a reduced graphene oxide modified electrode. This electrode exhibited high electrocatalytic activity towards glucose oxidation without use of any enzym...

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Main Authors: Liu, Yang, Dong, Y., Guo, C., Cui, Z., Zheng, L., Li, C.
Format: Journal Article
Published: Wiley - VCH Verlag GmbH & Co. KGaA 2012
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/25711
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author Liu, Yang
Dong, Y.
Guo, C.
Cui, Z.
Zheng, L.
Li, C.
author_facet Liu, Yang
Dong, Y.
Guo, C.
Cui, Z.
Zheng, L.
Li, C.
author_sort Liu, Yang
building Curtin Institutional Repository
collection Online Access
description A novel nonenzymatic glucose sensor was developed based on well-dispersed gold nanoparticles, which were in situ grown under direction of protein on a reduced graphene oxide modified electrode. This electrode exhibited high electrocatalytic activity towards glucose oxidation without use of any enzyme or mediator. In application for the amperometric detection of glucose, a wide linear range of 0.02–16.6 mM, low detection limit of 5 µM and good selectivity were obtained. The attractive analytical performances of the proposed glucose sensor, coupled with the facile preparation method, provide a promising electrochemical platform for the development of effective nonenzymatic sensors.
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format Journal Article
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T07:58:13Z
publishDate 2012
publisher Wiley - VCH Verlag GmbH & Co. KGaA
recordtype eprints
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spelling curtin-20.500.11937-257112017-09-13T15:17:10Z Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing Liu, Yang Dong, Y. Guo, C. Cui, Z. Zheng, L. Li, C. Nonenzymatic sensors Glucose Proteins Gold nanoparticles Reduced graphene oxide A novel nonenzymatic glucose sensor was developed based on well-dispersed gold nanoparticles, which were in situ grown under direction of protein on a reduced graphene oxide modified electrode. This electrode exhibited high electrocatalytic activity towards glucose oxidation without use of any enzyme or mediator. In application for the amperometric detection of glucose, a wide linear range of 0.02–16.6 mM, low detection limit of 5 µM and good selectivity were obtained. The attractive analytical performances of the proposed glucose sensor, coupled with the facile preparation method, provide a promising electrochemical platform for the development of effective nonenzymatic sensors. 2012 Journal Article http://hdl.handle.net/20.500.11937/25711 10.1002/elan.201200472 Wiley - VCH Verlag GmbH & Co. KGaA restricted
spellingShingle Nonenzymatic sensors
Glucose
Proteins
Gold nanoparticles
Reduced graphene oxide
Liu, Yang
Dong, Y.
Guo, C.
Cui, Z.
Zheng, L.
Li, C.
Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing
title Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing
title_full Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing
title_fullStr Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing
title_full_unstemmed Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing
title_short Protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing
title_sort protein-directed in situ synthesis of gold nanoparticles on reduced graphene oxide modified electrode for nonenzymatic glucose sensing
topic Nonenzymatic sensors
Glucose
Proteins
Gold nanoparticles
Reduced graphene oxide
url http://hdl.handle.net/20.500.11937/25711