Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor ß (TR-ß) selective ligands

Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor ß (TR-ß) selective ligands

Design and synthesis of a novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives are reported and their in vitro thyroid hormone receptor selectivity has been evaluated in the thyroid luciferase receptor assay. The 3-[3,5-dichloro-4-(4-hydroxy-3-isopropylphenoxy)-phenylamino]-4-hydroxy- cyclobut-3-ene...

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Bibliographic Details
Main Authors: Raval, S., Raval, P., Bandyopadhyay, D., Soni, K., Yevale, D., Jogiya, D., Modi, H., Joharapurkar, A., Gandhi, Neha, Jain, M., Patel, P.
Format: Journal Article
Published: Pergamon 2008
Online Access:http://hdl.handle.net/20.500.11937/25636

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