Segmentation of the mouse hippocampal formation in magnetic resonance images
The hippocampal formation plays an important role in cognition, spatial navigation, learning, and memory. High resolution magnetic resonance (MR) imaging makes it possible to study in vivo changes in the hippocampus over time and is useful for comparing hippocampal volume and structure in wild type...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Journal Article |
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Academic Press
2011
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/25533 |
| _version_ | 1848751735890247680 |
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| author | Richards, K. Watson, Charles Buckley, R. Kurniawan, N. Yang, Z. Keller, M. Beare, R. Bartlett, P. Egan, G. Galloway, G. Paxinos, G. Petrou, S. Reutens, D. |
| author_facet | Richards, K. Watson, Charles Buckley, R. Kurniawan, N. Yang, Z. Keller, M. Beare, R. Bartlett, P. Egan, G. Galloway, G. Paxinos, G. Petrou, S. Reutens, D. |
| author_sort | Richards, K. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The hippocampal formation plays an important role in cognition, spatial navigation, learning, and memory. High resolution magnetic resonance (MR) imaging makes it possible to study in vivo changes in the hippocampus over time and is useful for comparing hippocampal volume and structure in wild type and mutant mice. Such comparisons demand a reliable way to segment the hippocampal formation. We have developed a method for the systematic segmentation of the hippocampal formation using the perfusion-fixed C57BL/6 mouse brain for application in longitudinal and comparative studies. Our aim was to develop a guide for segmenting over 40 structures in an adult mouse brain using 30 μm isotropic resolution images acquired with a 16.4 T MR imaging system and combined using super-resolution reconstruction. |
| first_indexed | 2025-11-14T07:57:27Z |
| format | Journal Article |
| id | curtin-20.500.11937-25533 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:57:27Z |
| publishDate | 2011 |
| publisher | Academic Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-255332017-09-13T16:08:46Z Segmentation of the mouse hippocampal formation in magnetic resonance images Richards, K. Watson, Charles Buckley, R. Kurniawan, N. Yang, Z. Keller, M. Beare, R. Bartlett, P. Egan, G. Galloway, G. Paxinos, G. Petrou, S. Reutens, D. mouse brain CA fields perirhinal entorhinal hippocampus subiculum segmentation magnetic resonance hippocampal formation atlas The hippocampal formation plays an important role in cognition, spatial navigation, learning, and memory. High resolution magnetic resonance (MR) imaging makes it possible to study in vivo changes in the hippocampus over time and is useful for comparing hippocampal volume and structure in wild type and mutant mice. Such comparisons demand a reliable way to segment the hippocampal formation. We have developed a method for the systematic segmentation of the hippocampal formation using the perfusion-fixed C57BL/6 mouse brain for application in longitudinal and comparative studies. Our aim was to develop a guide for segmenting over 40 structures in an adult mouse brain using 30 μm isotropic resolution images acquired with a 16.4 T MR imaging system and combined using super-resolution reconstruction. 2011 Journal Article http://hdl.handle.net/20.500.11937/25533 10.1016/j.neuroimage.2011.06.025 Academic Press restricted |
| spellingShingle | mouse brain CA fields perirhinal entorhinal hippocampus subiculum segmentation magnetic resonance hippocampal formation atlas Richards, K. Watson, Charles Buckley, R. Kurniawan, N. Yang, Z. Keller, M. Beare, R. Bartlett, P. Egan, G. Galloway, G. Paxinos, G. Petrou, S. Reutens, D. Segmentation of the mouse hippocampal formation in magnetic resonance images |
| title | Segmentation of the mouse hippocampal formation in magnetic resonance images |
| title_full | Segmentation of the mouse hippocampal formation in magnetic resonance images |
| title_fullStr | Segmentation of the mouse hippocampal formation in magnetic resonance images |
| title_full_unstemmed | Segmentation of the mouse hippocampal formation in magnetic resonance images |
| title_short | Segmentation of the mouse hippocampal formation in magnetic resonance images |
| title_sort | segmentation of the mouse hippocampal formation in magnetic resonance images |
| topic | mouse brain CA fields perirhinal entorhinal hippocampus subiculum segmentation magnetic resonance hippocampal formation atlas |
| url | http://hdl.handle.net/20.500.11937/25533 |