The association of metabolic syndrome and aging with cognition in Asian men

Background: The present cross-sectional study examined the associations of individual metabolic factors and age with the short-term memory and perceptual capacity in 472 healthy Asian men. Methods: The symbol digit and digit span tests from the Swedish Performance Evaluation System were used to asse...

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Main Authors: Goh, Victor, Hart, William
Format: Journal Article
Published: Informa Healthcare 2014
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/25181
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author Goh, Victor
Hart, William
author_facet Goh, Victor
Hart, William
author_sort Goh, Victor
building Curtin Institutional Repository
collection Online Access
description Background: The present cross-sectional study examined the associations of individual metabolic factors and age with the short-term memory and perceptual capacity in 472 healthy Asian men. Methods: The symbol digit and digit span tests from the Swedish Performance Evaluation System were used to assess the perceptual capacity and memory cognitive domains. Linear regression with the stepwise method, and multivariate analyses of the General Linear Model with the Bonferroni correction for multiple comparisons were carried out with the SPSS 21.0 package. Results: High blood pressure and HDL were not significantly associated with either short-term memory or perceptual capacity. Age and glucose level were negatively associated but regular physical exercise was positively associated with perceptual capacity. On the other hand, high triglyceride level (TG) was positively associated but high waist/height ratio was negatively associated with short-term memory. When men without any component of the metabolic syndrome (MetS) were compared with men with one, two or three or more components of MetS, no significant differences in cognitive performance were noted. Conclusion: Not all the metabolic factors were significantly associated with short-term memory or the perceptual capacity domains. Those that were did not show a sufficiently consistent pattern of association to support a role for MetS as a whole in cognitive decline with aging. It may not be meaningful to evaluate the association of MetS as a whole with cognition.
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spelling curtin-20.500.11937-251812017-09-13T15:20:56Z The association of metabolic syndrome and aging with cognition in Asian men Goh, Victor Hart, William short-term memory metabolic syndrome Aging Asian men perceptual capacity Background: The present cross-sectional study examined the associations of individual metabolic factors and age with the short-term memory and perceptual capacity in 472 healthy Asian men. Methods: The symbol digit and digit span tests from the Swedish Performance Evaluation System were used to assess the perceptual capacity and memory cognitive domains. Linear regression with the stepwise method, and multivariate analyses of the General Linear Model with the Bonferroni correction for multiple comparisons were carried out with the SPSS 21.0 package. Results: High blood pressure and HDL were not significantly associated with either short-term memory or perceptual capacity. Age and glucose level were negatively associated but regular physical exercise was positively associated with perceptual capacity. On the other hand, high triglyceride level (TG) was positively associated but high waist/height ratio was negatively associated with short-term memory. When men without any component of the metabolic syndrome (MetS) were compared with men with one, two or three or more components of MetS, no significant differences in cognitive performance were noted. Conclusion: Not all the metabolic factors were significantly associated with short-term memory or the perceptual capacity domains. Those that were did not show a sufficiently consistent pattern of association to support a role for MetS as a whole in cognitive decline with aging. It may not be meaningful to evaluate the association of MetS as a whole with cognition. 2014 Journal Article http://hdl.handle.net/20.500.11937/25181 10.3109/13685538.2014.968772 Informa Healthcare fulltext
spellingShingle short-term memory
metabolic syndrome
Aging
Asian men
perceptual capacity
Goh, Victor
Hart, William
The association of metabolic syndrome and aging with cognition in Asian men
title The association of metabolic syndrome and aging with cognition in Asian men
title_full The association of metabolic syndrome and aging with cognition in Asian men
title_fullStr The association of metabolic syndrome and aging with cognition in Asian men
title_full_unstemmed The association of metabolic syndrome and aging with cognition in Asian men
title_short The association of metabolic syndrome and aging with cognition in Asian men
title_sort association of metabolic syndrome and aging with cognition in asian men
topic short-term memory
metabolic syndrome
Aging
Asian men
perceptual capacity
url http://hdl.handle.net/20.500.11937/25181