Cyclic and pulse voltammetric study of dopamine at the interface between two immiscible electrolyte solutions
The detection of dopamine by differential pulse voltammetry (DPV) and square wave voltammetry (SWV) at the interface between two immiscible electrolyte solutions (ITIES) has been studied. Voltammetry at the liquid/liquid (water/1,2-dichloroethane) interface provides a simple method for overcoming...
| Main Authors: | , , |
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| Format: | Journal Article |
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Elsevier BV
2005
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0956566304003690 http://hdl.handle.net/20.500.11937/24132 |
| _version_ | 1848751344061513728 |
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| author | Beni, V. Ghita, M. Arrigan, Damien |
| author_facet | Beni, V. Ghita, M. Arrigan, Damien |
| author_sort | Beni, V. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The detection of dopamine by differential pulse voltammetry (DPV) and square wave voltammetry (SWV) at the interface between two immiscible electrolyte solutions (ITIES) has been studied. Voltammetry at the liquid/liquid (water/1,2-dichloroethane) interface provides a simple method for overcoming the major problem associated with dopamine detection by voltammetry at solid electrodes: the co-existence of ascorbate at higher concentrations. Selectivity for dopamine was achieved by the use of dibenzo-18-crown-6 as an ionophore for the facilitated transfer voltammetry of protonated dopamine across the ITIES. Under these conditions, ascorbate is not transferred and hence does not interfere in the ion transfer current for dopamine. By use of DPV and SWV, the lowest concentration detectable can be lowered from ca. 0.1mM (obtained with cyclic voltammetry) to 2 M. Evaluation of the effect of some other physiologically important species (acetylcholine, sodium, potassium and ammonium ions) on the dopamine transfer voltammetry has been studied, indicating the need for improved ionophore designs in order to achieve practically useful selectivity. |
| first_indexed | 2025-11-14T07:51:14Z |
| format | Journal Article |
| id | curtin-20.500.11937-24132 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:51:14Z |
| publishDate | 2005 |
| publisher | Elsevier BV |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-241322017-09-13T13:58:22Z Cyclic and pulse voltammetric study of dopamine at the interface between two immiscible electrolyte solutions Beni, V. Ghita, M. Arrigan, Damien Dopamine Ascorbate Differential pulse voltammetry ITIES Square wave voltammetry Selectivity The detection of dopamine by differential pulse voltammetry (DPV) and square wave voltammetry (SWV) at the interface between two immiscible electrolyte solutions (ITIES) has been studied. Voltammetry at the liquid/liquid (water/1,2-dichloroethane) interface provides a simple method for overcoming the major problem associated with dopamine detection by voltammetry at solid electrodes: the co-existence of ascorbate at higher concentrations. Selectivity for dopamine was achieved by the use of dibenzo-18-crown-6 as an ionophore for the facilitated transfer voltammetry of protonated dopamine across the ITIES. Under these conditions, ascorbate is not transferred and hence does not interfere in the ion transfer current for dopamine. By use of DPV and SWV, the lowest concentration detectable can be lowered from ca. 0.1mM (obtained with cyclic voltammetry) to 2 M. Evaluation of the effect of some other physiologically important species (acetylcholine, sodium, potassium and ammonium ions) on the dopamine transfer voltammetry has been studied, indicating the need for improved ionophore designs in order to achieve practically useful selectivity. 2005 Journal Article http://hdl.handle.net/20.500.11937/24132 10.1016/j.bios.2004.08.004 http://www.sciencedirect.com/science/article/pii/S0956566304003690 Elsevier BV restricted |
| spellingShingle | Dopamine Ascorbate Differential pulse voltammetry ITIES Square wave voltammetry Selectivity Beni, V. Ghita, M. Arrigan, Damien Cyclic and pulse voltammetric study of dopamine at the interface between two immiscible electrolyte solutions |
| title | Cyclic and pulse voltammetric study of dopamine at the interface between two immiscible electrolyte solutions |
| title_full | Cyclic and pulse voltammetric study of dopamine at the interface between two immiscible electrolyte solutions |
| title_fullStr | Cyclic and pulse voltammetric study of dopamine at the interface between two immiscible electrolyte solutions |
| title_full_unstemmed | Cyclic and pulse voltammetric study of dopamine at the interface between two immiscible electrolyte solutions |
| title_short | Cyclic and pulse voltammetric study of dopamine at the interface between two immiscible electrolyte solutions |
| title_sort | cyclic and pulse voltammetric study of dopamine at the interface between two immiscible electrolyte solutions |
| topic | Dopamine Ascorbate Differential pulse voltammetry ITIES Square wave voltammetry Selectivity |
| url | http://www.sciencedirect.com/science/article/pii/S0956566304003690 http://hdl.handle.net/20.500.11937/24132 |