Community-onset Staphylococcus aureus infections presenting to general practices in South-eastern Australia
Community-acquired Staphylococcus aureus infections are a public health concern, yet little is known about infections that do not present to hospital. We identified community-onset S. aureus infections via specimens submitted to a community-based pathology service. Referring doctors confirmed eligib...
| Main Authors: | , , , , , , |
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| Format: | Journal Article |
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Cambridge University Press
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/24001 |
| _version_ | 1848751307833212928 |
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| author | Bennett, C. Coombs, Geoffrey Wood, G. Howden, B. Johnson, L. White, D. Johnson, P. |
| author_facet | Bennett, C. Coombs, Geoffrey Wood, G. Howden, B. Johnson, L. White, D. Johnson, P. |
| author_sort | Bennett, C. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Community-acquired Staphylococcus aureus infections are a public health concern, yet little is known about infections that do not present to hospital. We identified community-onset S. aureus infections via specimens submitted to a community-based pathology service. Referring doctors confirmed eligibility and described infection site, severity and treatment. Isolates were characterized on antibiotic resistance, PFGE, MLST/SCCmec, and Panton–Valentine leukocidin (PVL), representing 106 community-onset infections; 34 non-multiresistant methicillin-resistant S. aureus (nmMRSA) (resistant to <3 non-β-lactam antibiotics), 15 multiply antibiotic-resistant MRSA (mMRSA) and 57 methicillin-sensitive S. aureus (MSSA). Most (93%) were skin and soft tissue infections. PVL genes were carried by 42% of nmMRSA isolates [95% confidence interval (CI) 26–61] and 15% of MSSA (95% CI 8–28). PVL was associated with infections of the trunk, head or neck (56•4% vs. 24•3%, P = 0•005) in younger patients (23 vs. 52 years, P < 0•001), and with boils or abscesses (OR 8•67, 95% CI 2•9–26•2), suggesting underlying differences in exposure and/or pathogenesis. |
| first_indexed | 2025-11-14T07:50:39Z |
| format | Journal Article |
| id | curtin-20.500.11937-24001 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:50:39Z |
| publishDate | 2013 |
| publisher | Cambridge University Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-240012017-09-13T13:55:44Z Community-onset Staphylococcus aureus infections presenting to general practices in South-eastern Australia Bennett, C. Coombs, Geoffrey Wood, G. Howden, B. Johnson, L. White, D. Johnson, P. public health emerging infections staphylococcal infections methicillin-resistant S. aureus (MRSA) Epidemiology Staphylococcus aureus Community-acquired Staphylococcus aureus infections are a public health concern, yet little is known about infections that do not present to hospital. We identified community-onset S. aureus infections via specimens submitted to a community-based pathology service. Referring doctors confirmed eligibility and described infection site, severity and treatment. Isolates were characterized on antibiotic resistance, PFGE, MLST/SCCmec, and Panton–Valentine leukocidin (PVL), representing 106 community-onset infections; 34 non-multiresistant methicillin-resistant S. aureus (nmMRSA) (resistant to <3 non-β-lactam antibiotics), 15 multiply antibiotic-resistant MRSA (mMRSA) and 57 methicillin-sensitive S. aureus (MSSA). Most (93%) were skin and soft tissue infections. PVL genes were carried by 42% of nmMRSA isolates [95% confidence interval (CI) 26–61] and 15% of MSSA (95% CI 8–28). PVL was associated with infections of the trunk, head or neck (56•4% vs. 24•3%, P = 0•005) in younger patients (23 vs. 52 years, P < 0•001), and with boils or abscesses (OR 8•67, 95% CI 2•9–26•2), suggesting underlying differences in exposure and/or pathogenesis. 2013 Journal Article http://hdl.handle.net/20.500.11937/24001 10.1017/S0950268813001581 Cambridge University Press fulltext |
| spellingShingle | public health emerging infections staphylococcal infections methicillin-resistant S. aureus (MRSA) Epidemiology Staphylococcus aureus Bennett, C. Coombs, Geoffrey Wood, G. Howden, B. Johnson, L. White, D. Johnson, P. Community-onset Staphylococcus aureus infections presenting to general practices in South-eastern Australia |
| title | Community-onset Staphylococcus aureus infections presenting to general practices in South-eastern Australia |
| title_full | Community-onset Staphylococcus aureus infections presenting to general practices in South-eastern Australia |
| title_fullStr | Community-onset Staphylococcus aureus infections presenting to general practices in South-eastern Australia |
| title_full_unstemmed | Community-onset Staphylococcus aureus infections presenting to general practices in South-eastern Australia |
| title_short | Community-onset Staphylococcus aureus infections presenting to general practices in South-eastern Australia |
| title_sort | community-onset staphylococcus aureus infections presenting to general practices in south-eastern australia |
| topic | public health emerging infections staphylococcal infections methicillin-resistant S. aureus (MRSA) Epidemiology Staphylococcus aureus |
| url | http://hdl.handle.net/20.500.11937/24001 |