Calcium and Vitamin D modulate postprandial vascular function: A pilot dose-response study
Background: Calcium and vitamin D may modulate postprandial endothelial function. Subjects and Methods: Seven lean, young males completed a single blind randomized crossover design where they consumed three breakfast meals containing varying calcium and vitamin D (meal 1 ~200 mg/15 IU, meal 2 ~450 m...
| Main Authors: | , , |
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| Format: | Journal Article |
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WB Saunders Co.
2010
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| Online Access: | http://hdl.handle.net/20.500.11937/23777 |
| _version_ | 1848751244875661312 |
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| author | Soares, Mario Kuriyan, R. Kurpad, A. |
| author_facet | Soares, Mario Kuriyan, R. Kurpad, A. |
| author_sort | Soares, Mario |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: Calcium and vitamin D may modulate postprandial endothelial function. Subjects and Methods: Seven lean, young males completed a single blind randomized crossover design where they consumed three breakfast meals containing varying calcium and vitamin D (meal 1 ~200 mg/15 IU, meal 2 ~450 mg/140 IU, and meal 3 ~700 mg/265 IU). Stiffness index (SI), reflective index (RI) and pulse rate (PR) were serially assessed from the digital volume pulse by photoplethysmography (Pulse Trace PT-1000, Micro Medical, UK). Results: Incremental areas under the curve over 3 h (Δ) were analyzed by repeated measures ANOVA. ΔPTH was significantly less suppressed with meal A than with meal B and C (P = 0.003). In contrast, ΔRI was significantly more suppressed following meal A than with either meal B or C (P = 0.021). ΔSI did not change with meal ingestion and there was no difference in the rise of Δglucose, Δinsulin and ΔPR between meals. Conclusion: Higher calcium and vitamin D at breakfast prevented the fall in postprandial vascular tone without changes in glucose or insulin. |
| first_indexed | 2025-11-14T07:49:39Z |
| format | Journal Article |
| id | curtin-20.500.11937-23777 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:49:39Z |
| publishDate | 2010 |
| publisher | WB Saunders Co. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-237772017-09-13T15:59:27Z Calcium and Vitamin D modulate postprandial vascular function: A pilot dose-response study Soares, Mario Kuriyan, R. Kurpad, A. Background: Calcium and vitamin D may modulate postprandial endothelial function. Subjects and Methods: Seven lean, young males completed a single blind randomized crossover design where they consumed three breakfast meals containing varying calcium and vitamin D (meal 1 ~200 mg/15 IU, meal 2 ~450 mg/140 IU, and meal 3 ~700 mg/265 IU). Stiffness index (SI), reflective index (RI) and pulse rate (PR) were serially assessed from the digital volume pulse by photoplethysmography (Pulse Trace PT-1000, Micro Medical, UK). Results: Incremental areas under the curve over 3 h (Δ) were analyzed by repeated measures ANOVA. ΔPTH was significantly less suppressed with meal A than with meal B and C (P = 0.003). In contrast, ΔRI was significantly more suppressed following meal A than with either meal B or C (P = 0.021). ΔSI did not change with meal ingestion and there was no difference in the rise of Δglucose, Δinsulin and ΔPR between meals. Conclusion: Higher calcium and vitamin D at breakfast prevented the fall in postprandial vascular tone without changes in glucose or insulin. 2010 Journal Article http://hdl.handle.net/20.500.11937/23777 10.1016/j.dsx.2010.07.006 WB Saunders Co. restricted |
| spellingShingle | Soares, Mario Kuriyan, R. Kurpad, A. Calcium and Vitamin D modulate postprandial vascular function: A pilot dose-response study |
| title | Calcium and Vitamin D modulate postprandial vascular function: A pilot dose-response study |
| title_full | Calcium and Vitamin D modulate postprandial vascular function: A pilot dose-response study |
| title_fullStr | Calcium and Vitamin D modulate postprandial vascular function: A pilot dose-response study |
| title_full_unstemmed | Calcium and Vitamin D modulate postprandial vascular function: A pilot dose-response study |
| title_short | Calcium and Vitamin D modulate postprandial vascular function: A pilot dose-response study |
| title_sort | calcium and vitamin d modulate postprandial vascular function: a pilot dose-response study |
| url | http://hdl.handle.net/20.500.11937/23777 |