Significance of Coronary Calcification for Prediction of Coronary Artery Disease and Cardiac Events Based on 64-Slice Coronary Computed Tomography Angiography
This work aims to validate the clinical significance of coronary artery calcium score (CACS) in predicting coronary artery disease(CAD) and cardiac events in 100 symptomatic patients (aged 37–87 years, mean 62.5, 81 males) that were followed up for a mean of 5 years. Our results showed that patients...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
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Hindawi Publishing Corporation
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/23752 |
| _version_ | 1848751237905776640 |
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| author | Liu, Yuan-Chang Sun, Zhonghua Tsay, Pei-Kwei Tiffany, Chan Hsieh, I-Chang Chen, Chun-Chi Wen, Ming-Shien Wan, Yung-Liang |
| author_facet | Liu, Yuan-Chang Sun, Zhonghua Tsay, Pei-Kwei Tiffany, Chan Hsieh, I-Chang Chen, Chun-Chi Wen, Ming-Shien Wan, Yung-Liang |
| author_sort | Liu, Yuan-Chang |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | This work aims to validate the clinical significance of coronary artery calcium score (CACS) in predicting coronary artery disease(CAD) and cardiac events in 100 symptomatic patients (aged 37–87 years, mean 62.5, 81 males) that were followed up for a mean of 5 years. Our results showed that patients with CAD and cardiac events had significantly higher CACS than those without CAD and cardiac events, respectively. The corresponding data were 1450.42 ± 3471.24 versus 130 ± 188.29 (P < 0.001) for CAD, and1558.67 ± 513.29 versus 400.46 ± 104.47 (P = 0.031) for cardiac events. Of 72 patients with CAD, cardiac events were found in 56 (77.7%) patients. The prevalence of cardiac events in our cohort was 13.3% for calcium score 0, 50% for score 11–100, 56% for score 101–400, 68.7% for score 401–1,000, and 75.0% for score >1000. Increased CACS (>100)was also associated with an increased frequency of multi-vessel disease. Nonetheless, 3 (20%) out of 15 patients with zero CACS had single-vessel disease. Significant correlation (P < 0.001) was observed between CACS and CAD on a vessel-based analysis for coronary arteries. It is concluded that CACS is significantly correlated with CAD and cardiac events. |
| first_indexed | 2025-11-14T07:49:32Z |
| format | Journal Article |
| id | curtin-20.500.11937-23752 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:49:32Z |
| publishDate | 2013 |
| publisher | Hindawi Publishing Corporation |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-237522017-09-13T14:00:17Z Significance of Coronary Calcification for Prediction of Coronary Artery Disease and Cardiac Events Based on 64-Slice Coronary Computed Tomography Angiography Liu, Yuan-Chang Sun, Zhonghua Tsay, Pei-Kwei Tiffany, Chan Hsieh, I-Chang Chen, Chun-Chi Wen, Ming-Shien Wan, Yung-Liang calcium score Coronary artery disease mortality coronary CT This work aims to validate the clinical significance of coronary artery calcium score (CACS) in predicting coronary artery disease(CAD) and cardiac events in 100 symptomatic patients (aged 37–87 years, mean 62.5, 81 males) that were followed up for a mean of 5 years. Our results showed that patients with CAD and cardiac events had significantly higher CACS than those without CAD and cardiac events, respectively. The corresponding data were 1450.42 ± 3471.24 versus 130 ± 188.29 (P < 0.001) for CAD, and1558.67 ± 513.29 versus 400.46 ± 104.47 (P = 0.031) for cardiac events. Of 72 patients with CAD, cardiac events were found in 56 (77.7%) patients. The prevalence of cardiac events in our cohort was 13.3% for calcium score 0, 50% for score 11–100, 56% for score 101–400, 68.7% for score 401–1,000, and 75.0% for score >1000. Increased CACS (>100)was also associated with an increased frequency of multi-vessel disease. Nonetheless, 3 (20%) out of 15 patients with zero CACS had single-vessel disease. Significant correlation (P < 0.001) was observed between CACS and CAD on a vessel-based analysis for coronary arteries. It is concluded that CACS is significantly correlated with CAD and cardiac events. 2013 Journal Article http://hdl.handle.net/20.500.11937/23752 10.1155/2013/472347 Hindawi Publishing Corporation fulltext |
| spellingShingle | calcium score Coronary artery disease mortality coronary CT Liu, Yuan-Chang Sun, Zhonghua Tsay, Pei-Kwei Tiffany, Chan Hsieh, I-Chang Chen, Chun-Chi Wen, Ming-Shien Wan, Yung-Liang Significance of Coronary Calcification for Prediction of Coronary Artery Disease and Cardiac Events Based on 64-Slice Coronary Computed Tomography Angiography |
| title | Significance of Coronary Calcification for Prediction of Coronary Artery Disease and Cardiac Events Based on 64-Slice Coronary Computed Tomography Angiography |
| title_full | Significance of Coronary Calcification for Prediction of Coronary Artery Disease and Cardiac Events Based on 64-Slice Coronary Computed Tomography Angiography |
| title_fullStr | Significance of Coronary Calcification for Prediction of Coronary Artery Disease and Cardiac Events Based on 64-Slice Coronary Computed Tomography Angiography |
| title_full_unstemmed | Significance of Coronary Calcification for Prediction of Coronary Artery Disease and Cardiac Events Based on 64-Slice Coronary Computed Tomography Angiography |
| title_short | Significance of Coronary Calcification for Prediction of Coronary Artery Disease and Cardiac Events Based on 64-Slice Coronary Computed Tomography Angiography |
| title_sort | significance of coronary calcification for prediction of coronary artery disease and cardiac events based on 64-slice coronary computed tomography angiography |
| topic | calcium score Coronary artery disease mortality coronary CT |
| url | http://hdl.handle.net/20.500.11937/23752 |