Cyclization enhances function of linear anti-arthritic peptides

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Cyclization enhances function of linear anti-arthritic peptides

This study describes the biophysical and immunomodulatory features of a cyclic peptide termed C1 which consists of alternating d-, l-amino acids and is capable of inhibiting IL-2 production in vitro and reducing the induction and extent of T-cell mediated inflammation in animal models. Solid-state n...

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Bibliographic Details
Main Authors:	Ali, Marina, Amon, Michael, Bender, Vera, Bolte, Andrea, Separovic, Frances, Benson, Heather, Manolios, Nicholas
Format:	Journal Article
Published:	Academic Press 2014
Subjects:	Arthritis T cells Asthma Peptides NMR Inflammation
Online Access:	http://hdl.handle.net/20.500.11937/23307

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