Liquid and Thin-Layer Chromatography
Liquid chromatography is a broad classification used to describe a variety of different chromatographic configurations that rely on the use of a liquid mobile phase. Paper, thin-layer, and classical column chromatography techniques, as well as high-performance liquid chromatography (HPLC) and ion ch...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Book Chapter |
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Academic Press
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/23017 |
| _version_ | 1848751033814089728 |
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| author | Lewis, Simon Lenehan, C. |
| author2 | Jay A Siegel |
| author_facet | Jay A Siegel Lewis, Simon Lenehan, C. |
| author_sort | Lewis, Simon |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Liquid chromatography is a broad classification used to describe a variety of different chromatographic configurations that rely on the use of a liquid mobile phase. Paper, thin-layer, and classical column chromatography techniques, as well as high-performance liquid chromatography (HPLC) and ion chromatography, all belong to the class of liquid chromatography. These techniques are heavily used in forensic science to separate a wide range of analytes including, but not restricted to, illicit drugs, drugs, and drug metabolites in toxicology samples, explosives residues, and textile fiber dyes. A variety of separation mechanisms can be used within liquid chromatography; these include adsorption, ion-exchange, size-exclusion, affinity, and ion-pair formation. A discussion of these separation mechanisms can be found in Chromatography: Basic Principles. This article gives an overview of classical, high-performance, and thin-layer chromatographic techniques including experimental configurations and forensic applications. |
| first_indexed | 2025-11-14T07:46:18Z |
| format | Book Chapter |
| id | curtin-20.500.11937-23017 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:46:18Z |
| publishDate | 2013 |
| publisher | Academic Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-230172023-02-08T04:12:04Z Liquid and Thin-Layer Chromatography Lewis, Simon Lenehan, C. Jay A Siegel Pekka J Saukko Liquid chromatography is a broad classification used to describe a variety of different chromatographic configurations that rely on the use of a liquid mobile phase. Paper, thin-layer, and classical column chromatography techniques, as well as high-performance liquid chromatography (HPLC) and ion chromatography, all belong to the class of liquid chromatography. These techniques are heavily used in forensic science to separate a wide range of analytes including, but not restricted to, illicit drugs, drugs, and drug metabolites in toxicology samples, explosives residues, and textile fiber dyes. A variety of separation mechanisms can be used within liquid chromatography; these include adsorption, ion-exchange, size-exclusion, affinity, and ion-pair formation. A discussion of these separation mechanisms can be found in Chromatography: Basic Principles. This article gives an overview of classical, high-performance, and thin-layer chromatographic techniques including experimental configurations and forensic applications. 2013 Book Chapter http://hdl.handle.net/20.500.11937/23017 10.1016/B978-0-12-382165-2.00246-4 Academic Press restricted |
| spellingShingle | Lewis, Simon Lenehan, C. Liquid and Thin-Layer Chromatography |
| title | Liquid and Thin-Layer Chromatography |
| title_full | Liquid and Thin-Layer Chromatography |
| title_fullStr | Liquid and Thin-Layer Chromatography |
| title_full_unstemmed | Liquid and Thin-Layer Chromatography |
| title_short | Liquid and Thin-Layer Chromatography |
| title_sort | liquid and thin-layer chromatography |
| url | http://hdl.handle.net/20.500.11937/23017 |