Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge

Pathogen infection stimulates the fatty acid (FA) metabolism and the production of pro-inflammatory derivatives of FA. Barramundi, Lates calcarifer, was fed on a diet rich in preformed long-chain (=C20) polyunsaturated fatty acids (LC-PUFA) from fish oil (FO), to compare with diets containing high l...

Full description

Bibliographic Details
Main Authors: Alhazzaa, Ramez, Bridle, A., Mori, T., Barden, A., Nichols, P., Carter, C.
Format: Journal Article
Published: 2013
Online Access:http://hdl.handle.net/20.500.11937/22999
_version_ 1848751029501296640
author Alhazzaa, Ramez
Bridle, A.
Mori, T.
Barden, A.
Nichols, P.
Carter, C.
author_facet Alhazzaa, Ramez
Bridle, A.
Mori, T.
Barden, A.
Nichols, P.
Carter, C.
author_sort Alhazzaa, Ramez
building Curtin Institutional Repository
collection Online Access
description Pathogen infection stimulates the fatty acid (FA) metabolism and the production of pro-inflammatory derivatives of FA. Barramundi, Lates calcarifer, was fed on a diet rich in preformed long-chain (=C20) polyunsaturated fatty acids (LC-PUFA) from fish oil (FO), to compare with diets containing high levels of C18 precursors for LC-PUFA - stearidonic (SDA) and ?-linolenic acid (GLA) - from Echium plantagineum (EO), or rapeseed oil (RO) rich in a-linolenic acid (ALA), but a poor source of LC-PUFA and their precursors. After 6 weeks, when growth rates were similar amongst the dietary treatments, a sub-lethal dose of Streptococcus iniae was administered to half of the fish, while the other half were maintained unchallenged and were pair-fed with the infected fish. Under a disease challenge situation, the tissue FA depots depleted at 3 days post-infection (DPI) and were then restored to their previous concentrations at 7 DPI. During the infection period, EO fish had a higher content of n3 and n6 PUFA in their tissues, higher n3:n6 PUFA ratio and reduced levels of the eicosanoids, TXB 2 and 6-keto-PGF1a, in their plasma compared with RO fish. Fish fed on FO and EO had a longer lasting and enduring response in their FA and eicosanoid concentrations, following a week of bacterial infection, compared with those fed on RO. EO, containing SDA and GLA and with a comparatively higher n3:n6 PUFA ratio, proved more effective than RO in compensating for immunity stress. © 2013 Elsevier Ltd.
first_indexed 2025-11-14T07:46:14Z
format Journal Article
id curtin-20.500.11937-22999
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T07:46:14Z
publishDate 2013
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-229992017-09-13T13:59:01Z Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge Alhazzaa, Ramez Bridle, A. Mori, T. Barden, A. Nichols, P. Carter, C. Pathogen infection stimulates the fatty acid (FA) metabolism and the production of pro-inflammatory derivatives of FA. Barramundi, Lates calcarifer, was fed on a diet rich in preformed long-chain (=C20) polyunsaturated fatty acids (LC-PUFA) from fish oil (FO), to compare with diets containing high levels of C18 precursors for LC-PUFA - stearidonic (SDA) and ?-linolenic acid (GLA) - from Echium plantagineum (EO), or rapeseed oil (RO) rich in a-linolenic acid (ALA), but a poor source of LC-PUFA and their precursors. After 6 weeks, when growth rates were similar amongst the dietary treatments, a sub-lethal dose of Streptococcus iniae was administered to half of the fish, while the other half were maintained unchallenged and were pair-fed with the infected fish. Under a disease challenge situation, the tissue FA depots depleted at 3 days post-infection (DPI) and were then restored to their previous concentrations at 7 DPI. During the infection period, EO fish had a higher content of n3 and n6 PUFA in their tissues, higher n3:n6 PUFA ratio and reduced levels of the eicosanoids, TXB 2 and 6-keto-PGF1a, in their plasma compared with RO fish. Fish fed on FO and EO had a longer lasting and enduring response in their FA and eicosanoid concentrations, following a week of bacterial infection, compared with those fed on RO. EO, containing SDA and GLA and with a comparatively higher n3:n6 PUFA ratio, proved more effective than RO in compensating for immunity stress. © 2013 Elsevier Ltd. 2013 Journal Article http://hdl.handle.net/20.500.11937/22999 10.1016/j.foodchem.2013.04.052 restricted
spellingShingle Alhazzaa, Ramez
Bridle, A.
Mori, T.
Barden, A.
Nichols, P.
Carter, C.
Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge
title Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge
title_full Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge
title_fullStr Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge
title_full_unstemmed Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge
title_short Echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge
title_sort echium oil is better than rapeseed oil in improving the response of barramundi to a disease challenge
url http://hdl.handle.net/20.500.11937/22999