CT virtual intravascular endoscopy assessment of coronary artery plaques:A preliminary study

Purpose: The purpose of this study was to investigate the potential value of CT virtual intravascular endoscopy (VIE) in the visualization and assessment of coronary plaques in patients suspected of coronary artery disease.Materials and Methods: 20 (13 men, 7 women, mean age 54 years) consecutive pa...

Full description

Bibliographic Details
Main Authors: Sun, Zhonghua, Jacobus D., Nugrohob, J., Adipranotob, J.
Format: Journal Article
Published: Elsevier Ireland Ltd 2009
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/22728
_version_ 1848750951344635904
author Sun, Zhonghua
Jacobus D.
Nugrohob, J.
Adipranotob, J.
author_facet Sun, Zhonghua
Jacobus D.
Nugrohob, J.
Adipranotob, J.
author_sort Sun, Zhonghua
building Curtin Institutional Repository
collection Online Access
description Purpose: The purpose of this study was to investigate the potential value of CT virtual intravascular endoscopy (VIE) in the visualization and assessment of coronary plaques in patients suspected of coronary artery disease.Materials and Methods: 20 (13 men, 7 women, mean age 54 years) consecutive patients with suspected coronary artery disease undergoing 64-slice CT angiography were included in the study. Four main coronary artery branches were assessed with regard to the presence of coronary plaques based on 2D axial, multiplanar reformation, 3D volume rendering and VIE visualizations. The coronary plaques were characterized into calcified, noncalcified and mixed plaques. The intraluminal appearances of these coronary plaques were demonstrated with VIE images and correlated with 2D and 3D images to determine the diagnostic value of VIE for assessment of the plaques.Results: VIE was able to identify and demonstrate the intraluminal appearances of coronary plaques in 18 patients involving 32 coronary artery branches which was shown as an irregularly intraluminal protruding sign in extensively calcified plaques and smooth protruding appearance in noncalcified or focally calcifed plaques. An irregular intraluminal apearance was also noticed in the presence of mixed plaques due to variable components with different CT attenuation contained within the plaques. VIE accurately confirmed the degree of coronary stenosis or occlusion despite presence of heavy calcification.Conclusion: VIE could be used as a complementary tool to conventional CT visualizations for analysis of luminal changes and assessment of disease extent caused by the coronary plaques.
first_indexed 2025-11-14T07:44:59Z
format Journal Article
id curtin-20.500.11937-22728
institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T07:44:59Z
publishDate 2009
publisher Elsevier Ireland Ltd
recordtype eprints
repository_type Digital Repository
spelling curtin-20.500.11937-227282017-09-13T15:59:54Z CT virtual intravascular endoscopy assessment of coronary artery plaques:A preliminary study Sun, Zhonghua Jacobus D. Nugrohob, J. Adipranotob, J. virtual intravascular endoscopy coronary artery disease coronary plaque intraluminal appearance multislice computed tomography Purpose: The purpose of this study was to investigate the potential value of CT virtual intravascular endoscopy (VIE) in the visualization and assessment of coronary plaques in patients suspected of coronary artery disease.Materials and Methods: 20 (13 men, 7 women, mean age 54 years) consecutive patients with suspected coronary artery disease undergoing 64-slice CT angiography were included in the study. Four main coronary artery branches were assessed with regard to the presence of coronary plaques based on 2D axial, multiplanar reformation, 3D volume rendering and VIE visualizations. The coronary plaques were characterized into calcified, noncalcified and mixed plaques. The intraluminal appearances of these coronary plaques were demonstrated with VIE images and correlated with 2D and 3D images to determine the diagnostic value of VIE for assessment of the plaques.Results: VIE was able to identify and demonstrate the intraluminal appearances of coronary plaques in 18 patients involving 32 coronary artery branches which was shown as an irregularly intraluminal protruding sign in extensively calcified plaques and smooth protruding appearance in noncalcified or focally calcifed plaques. An irregular intraluminal apearance was also noticed in the presence of mixed plaques due to variable components with different CT attenuation contained within the plaques. VIE accurately confirmed the degree of coronary stenosis or occlusion despite presence of heavy calcification.Conclusion: VIE could be used as a complementary tool to conventional CT visualizations for analysis of luminal changes and assessment of disease extent caused by the coronary plaques. 2009 Journal Article http://hdl.handle.net/20.500.11937/22728 10.1016/j.ejrad.2009.09.007 Elsevier Ireland Ltd fulltext
spellingShingle virtual intravascular endoscopy
coronary artery disease
coronary plaque
intraluminal appearance
multislice computed tomography
Sun, Zhonghua
Jacobus D.
Nugrohob, J.
Adipranotob, J.
CT virtual intravascular endoscopy assessment of coronary artery plaques:A preliminary study
title CT virtual intravascular endoscopy assessment of coronary artery plaques:A preliminary study
title_full CT virtual intravascular endoscopy assessment of coronary artery plaques:A preliminary study
title_fullStr CT virtual intravascular endoscopy assessment of coronary artery plaques:A preliminary study
title_full_unstemmed CT virtual intravascular endoscopy assessment of coronary artery plaques:A preliminary study
title_short CT virtual intravascular endoscopy assessment of coronary artery plaques:A preliminary study
title_sort ct virtual intravascular endoscopy assessment of coronary artery plaques:a preliminary study
topic virtual intravascular endoscopy
coronary artery disease
coronary plaque
intraluminal appearance
multislice computed tomography
url http://hdl.handle.net/20.500.11937/22728