Optical coherence elastography: Strain imaging in tissue using optical coherence tomography

Optical coherence elastography (OCE) is a strain imaging technique that characterizes the elastic properties of tissues with microscopic resolution in three dimensions. In OCE, the displacement introduced to tissue by mechanical excitation is measured using optical coherence tomography. The local st...

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Main Authors: Kennedy, B., Kennedy, K., Ford, Christopher, McLaughlin, R., Bush, M., Sampson, D.
Other Authors: Yanbiao Liao
Format: Conference Paper
Published: SPIE 2012
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/22659
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author Kennedy, B.
Kennedy, K.
Ford, Christopher
McLaughlin, R.
Bush, M.
Sampson, D.
author2 Yanbiao Liao
author_facet Yanbiao Liao
Kennedy, B.
Kennedy, K.
Ford, Christopher
McLaughlin, R.
Bush, M.
Sampson, D.
author_sort Kennedy, B.
building Curtin Institutional Repository
collection Online Access
description Optical coherence elastography (OCE) is a strain imaging technique that characterizes the elastic properties of tissues with microscopic resolution in three dimensions. In OCE, the displacement introduced to tissue by mechanical excitation is measured using optical coherence tomography. The local strain is calculated from the spatial derivative of displacement to generate strain images, known as elastograms. To validate elastograms, we compare them to a finite element analysis model of sample deformation. We also present preliminary OCE measurements performed on excised human breast tissue, and demonstrate discrimination of tissue types based on their elastic properties.
first_indexed 2025-11-14T07:44:40Z
format Conference Paper
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T07:44:40Z
publishDate 2012
publisher SPIE
recordtype eprints
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spelling curtin-20.500.11937-226592023-02-02T07:57:40Z Optical coherence elastography: Strain imaging in tissue using optical coherence tomography Kennedy, B. Kennedy, K. Ford, Christopher McLaughlin, R. Bush, M. Sampson, D. Yanbiao Liao Wei Jin David D. Sampson Ryozo Yamauchi Youngjoo Chung Kentaro Nakamura Yunjiang Rao Finite element analysis Optical coherence tomography Strain Elastography Elastogram Optical coherence elastography (OCE) is a strain imaging technique that characterizes the elastic properties of tissues with microscopic resolution in three dimensions. In OCE, the displacement introduced to tissue by mechanical excitation is measured using optical coherence tomography. The local strain is calculated from the spatial derivative of displacement to generate strain images, known as elastograms. To validate elastograms, we compare them to a finite element analysis model of sample deformation. We also present preliminary OCE measurements performed on excised human breast tissue, and demonstrate discrimination of tissue types based on their elastic properties. 2012 Conference Paper http://hdl.handle.net/20.500.11937/22659 10.1117/12.975187 SPIE restricted
spellingShingle Finite element analysis
Optical coherence tomography
Strain
Elastography
Elastogram
Kennedy, B.
Kennedy, K.
Ford, Christopher
McLaughlin, R.
Bush, M.
Sampson, D.
Optical coherence elastography: Strain imaging in tissue using optical coherence tomography
title Optical coherence elastography: Strain imaging in tissue using optical coherence tomography
title_full Optical coherence elastography: Strain imaging in tissue using optical coherence tomography
title_fullStr Optical coherence elastography: Strain imaging in tissue using optical coherence tomography
title_full_unstemmed Optical coherence elastography: Strain imaging in tissue using optical coherence tomography
title_short Optical coherence elastography: Strain imaging in tissue using optical coherence tomography
title_sort optical coherence elastography: strain imaging in tissue using optical coherence tomography
topic Finite element analysis
Optical coherence tomography
Strain
Elastography
Elastogram
url http://hdl.handle.net/20.500.11937/22659