RAFT polymerization and thiol chemistry: A complementary pairing for implementing modern macromolecular design
Reversible addition fragmentation chain transfer (RAFT) polymerization is one of the most extensively studied reversible deactivation radical polymerization methods for the production of well-defined polymers. After polymerization, the RAFT agent end-group can easily be converted into a thiol, openi...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Published: |
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/22588 |
| _version_ | 1848750911881478144 |
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| author | Roth, P. Boyer, C. Lowe, Andrew Davis, T. |
| author_facet | Roth, P. Boyer, C. Lowe, Andrew Davis, T. |
| author_sort | Roth, P. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Reversible addition fragmentation chain transfer (RAFT) polymerization is one of the most extensively studied reversible deactivation radical polymerization methods for the production of well-defined polymers. After polymerization, the RAFT agent end-group can easily be converted into a thiol, opening manifold opportunities for thiol modification reactions. This review is focused both on the introduction of functional end-groups using well-established methods, such as thiol-ene chemistry, as well as on creating bio-cleavable disulfide linkages via disulfide exchange reactions. We demonstrate that thiol modification is a highly attractive and efficient chemistry for modifying RAFT polymers. |
| first_indexed | 2025-11-14T07:44:22Z |
| format | Journal Article |
| id | curtin-20.500.11937-22588 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:44:22Z |
| publishDate | 2011 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-225882017-09-13T13:55:44Z RAFT polymerization and thiol chemistry: A complementary pairing for implementing modern macromolecular design Roth, P. Boyer, C. Lowe, Andrew Davis, T. Reversible addition fragmentation chain transfer (RAFT) polymerization is one of the most extensively studied reversible deactivation radical polymerization methods for the production of well-defined polymers. After polymerization, the RAFT agent end-group can easily be converted into a thiol, opening manifold opportunities for thiol modification reactions. This review is focused both on the introduction of functional end-groups using well-established methods, such as thiol-ene chemistry, as well as on creating bio-cleavable disulfide linkages via disulfide exchange reactions. We demonstrate that thiol modification is a highly attractive and efficient chemistry for modifying RAFT polymers. 2011 Journal Article http://hdl.handle.net/20.500.11937/22588 10.1002/marc.201100127 restricted |
| spellingShingle | Roth, P. Boyer, C. Lowe, Andrew Davis, T. RAFT polymerization and thiol chemistry: A complementary pairing for implementing modern macromolecular design |
| title | RAFT polymerization and thiol chemistry: A complementary pairing for implementing modern macromolecular design |
| title_full | RAFT polymerization and thiol chemistry: A complementary pairing for implementing modern macromolecular design |
| title_fullStr | RAFT polymerization and thiol chemistry: A complementary pairing for implementing modern macromolecular design |
| title_full_unstemmed | RAFT polymerization and thiol chemistry: A complementary pairing for implementing modern macromolecular design |
| title_short | RAFT polymerization and thiol chemistry: A complementary pairing for implementing modern macromolecular design |
| title_sort | raft polymerization and thiol chemistry: a complementary pairing for implementing modern macromolecular design |
| url | http://hdl.handle.net/20.500.11937/22588 |