Electrochemical determination of L-Tryptophan, L-Tyrosine and L-Cysteine using electrospun carbon nanofibers modified electrode

A novel and simple method for the direct and quantitative determination of L-tryptophan (Trp), L-tyrosine (Tyr) and L-cysteine (Cys) was proposed in this work. Carbon nanofibers (CNFs), made by electrospinning technique, were used to modify carbon paste electrode (CPE) without any treatment to study...

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Main Authors: Tang, X., Liu, Yang, Hou, H., You, T.
Format: Journal Article
Published: Elsevier 2010
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/22498
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author Tang, X.
Liu, Yang
Hou, H.
You, T.
author_facet Tang, X.
Liu, Yang
Hou, H.
You, T.
author_sort Tang, X.
building Curtin Institutional Repository
collection Online Access
description A novel and simple method for the direct and quantitative determination of L-tryptophan (Trp), L-tyrosine (Tyr) and L-cysteine (Cys) was proposed in this work. Carbon nanofibers (CNFs), made by electrospinning technique, were used to modify carbon paste electrode (CPE) without any treatment to study the electrochemical behaviors of the three amino acids using cyclic voltammetry (CV) and constant potential amperometric method. The results demonstrated that the CNFs modified carbon paste electrode (CNFCPE) exhibited high electrocatalytic activity and good analytical performance towards the oxidation of the three amino acids. The linear ranges of Trp, Tyr and Cys were 0.1–119, 0.2–107 and 0.15–64Mwith correlation coefficients of 0.9994, 0.9985 and 0.9996, respectively. All the detection limits of the analytes were 0.1M(S/N = 3). In addition, the CNF-CPE displayed good reproducibility, high sensitivity and good selectivity towards the determination of the amino acids, making it suitable for the determination of Trp, Tyr and Cys in clinical and medicine.
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spelling curtin-20.500.11937-224982017-09-13T13:54:26Z Electrochemical determination of L-Tryptophan, L-Tyrosine and L-Cysteine using electrospun carbon nanofibers modified electrode Tang, X. Liu, Yang Hou, H. You, T. Tryptophan Modified electrode Cysteine Tyrosine Carbon nanofibers Electrocatalytic oxidation A novel and simple method for the direct and quantitative determination of L-tryptophan (Trp), L-tyrosine (Tyr) and L-cysteine (Cys) was proposed in this work. Carbon nanofibers (CNFs), made by electrospinning technique, were used to modify carbon paste electrode (CPE) without any treatment to study the electrochemical behaviors of the three amino acids using cyclic voltammetry (CV) and constant potential amperometric method. The results demonstrated that the CNFs modified carbon paste electrode (CNFCPE) exhibited high electrocatalytic activity and good analytical performance towards the oxidation of the three amino acids. The linear ranges of Trp, Tyr and Cys were 0.1–119, 0.2–107 and 0.15–64Mwith correlation coefficients of 0.9994, 0.9985 and 0.9996, respectively. All the detection limits of the analytes were 0.1M(S/N = 3). In addition, the CNF-CPE displayed good reproducibility, high sensitivity and good selectivity towards the determination of the amino acids, making it suitable for the determination of Trp, Tyr and Cys in clinical and medicine. 2010 Journal Article http://hdl.handle.net/20.500.11937/22498 10.1016/j.talanta.2009.11.027 Elsevier restricted
spellingShingle Tryptophan
Modified electrode
Cysteine
Tyrosine
Carbon nanofibers
Electrocatalytic oxidation
Tang, X.
Liu, Yang
Hou, H.
You, T.
Electrochemical determination of L-Tryptophan, L-Tyrosine and L-Cysteine using electrospun carbon nanofibers modified electrode
title Electrochemical determination of L-Tryptophan, L-Tyrosine and L-Cysteine using electrospun carbon nanofibers modified electrode
title_full Electrochemical determination of L-Tryptophan, L-Tyrosine and L-Cysteine using electrospun carbon nanofibers modified electrode
title_fullStr Electrochemical determination of L-Tryptophan, L-Tyrosine and L-Cysteine using electrospun carbon nanofibers modified electrode
title_full_unstemmed Electrochemical determination of L-Tryptophan, L-Tyrosine and L-Cysteine using electrospun carbon nanofibers modified electrode
title_short Electrochemical determination of L-Tryptophan, L-Tyrosine and L-Cysteine using electrospun carbon nanofibers modified electrode
title_sort electrochemical determination of l-tryptophan, l-tyrosine and l-cysteine using electrospun carbon nanofibers modified electrode
topic Tryptophan
Modified electrode
Cysteine
Tyrosine
Carbon nanofibers
Electrocatalytic oxidation
url http://hdl.handle.net/20.500.11937/22498