Analysis, regulation, and roles of endosomal phosphoinositides

QR Code

Analysis, regulation, and roles of endosomal phosphoinositides

Phosphoinositides (PIs) are minor lipid components of cellular membranes that play critical roles in membrane dynamics, trafficking, and cellular signaling. Among the seven naturally occurring PIs, the monophosphate phosphatidylinositol 3-phosphate (PtdIns3P) and the bisphosphate phosphatidylinosito...

Full description

Bibliographic Details
Main Authors:	Maffucci, T., Falasca, Marco
Format:	Book Chapter
Published:	Academic Press Inc. 2014
Online Access:	http://hdl.handle.net/20.500.11937/22458

Similar Items

Regulation and cellular functions of class II phosphoinositide 3-kinases
by: Falasca, Marco, et al.
Published: (2012)

New insight into the intracellular roles of class II phosphoinositide 3-kinases
by: Maffucci, T., et al.
Published: (2014)

Genetic and epigenetic regulation of phosphoinositide 3-kinase isoforms
by: Fyffe, C., et al.
Published: (2013)

Investigating the mechanisms of activation and action of phosphoinositide 3-kinase C2 alpha in pancreatic beta cells
by: Mazza, S., et al.
Published: (2013)

Novel roles for class II Phosphoinositide 3-Kinase C2ß in signalling pathways involved in prostate cancer cell invasion.
by: Mavrommati, I., et al.
Published: (2016)

Key role of phosphoinositide 3-kinase class IB in pancreatic cancer
by: Edling, C., et al.
Published: (2010)

A phosphoinositide 3-kinase/phospholipase cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation
by: Maffucci, T., et al.
Published: (2009)

Phosphoinositide 3-kinase pathway inhibitors: pharmacology, metabolism & drug development
by: Falasca, Marco
Published: (2011)

Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway
by: Edling, C., et al.
Published: (2014)

Phosphoinositides signalling in cancer: Focus on PI3K and PLC
by: Raimondi, C., et al.
Published: (2012)

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic ß cells
by: Dominguez, V., et al.
Published: (2011)

Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis
by: Tibolla, G., et al.
Published: (2013)

3-phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer
by: Fyffe, C., et al.
Published: (2013)

THE CLASS II PHOSPHOINOSITIDE 3-KINASE ISOFORM beta REGULATES PLATELET FUNCTION AND ARTERIAL THROMBOSIS IN MICE
by: Tibolla, G., et al.
Published: (2011)

mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate
by: Marat, A., et al.
Published: (2017)

Class II Phosphoinositide 3-Kinases as Novel Drug Targets
by: Falasca, Marco, et al.
Published: (2017)

Class II phosphoinositide 3-kinase C2ß regulates a novel signaling pathway involved in breast cancer progression.
by: Chikh, A., et al.
Published: (2016)

Sphingolipid metabolism in trans-golgi/endosomal membranes and the regulation of intracellular homeostatic processes in eukaryotic cells
by: Mousley, Carl, et al.
Published: (2010)

Targeting phosphoinositide 3-kinase pathways in pancreatic cancer - from molecular signalling to clinical trials
by: Falasca, Marco, et al.
Published: (2011)

Biosynthesis Of Endosome-Specific Lipid Bis(Monoacylglycero)Phosphate
by: Lim,, Shi Rou
Published: (2018)

Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts
by: Falasca, Marco, et al.
Published: (2014)

Rethinking phosphatidylinositol 3-monophosphate
by: Falasca, Marco, et al.
Published: (2009)

Functional Anatomy of Phospholipid Binding and Regulation of Phosphoinositide Homeostasis by Proteins of the Sec14 Superfamily
by: Schaaf, G., et al.
Published: (2008)

Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast
by: Mousley, Carl, et al.
Published: (2008)

Sec14 like PITPs couple lipid metabolism with phosphoinositide synthesis to regulate golgi functionality
by: Mousley, Carl, et al.
Published: (2015)

PI3K Class II [alpha] Controls Spatially Restricted Endosomal PtdIns3P and Rab11 Activation to Promote Primary Cilium Function
by: Franco, I., et al.
Published: (2014)

Cancer chemoprevention with nuts.
by: Falasca, Marco, et al.
Published: (2014)

The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation
by: Pieiro, R., et al.
Published: (2011)

Boyden chamber
by: Falasca, Marco, et al.
Published: (2011)

PITPs as targets for selectively interfering with phosphoinositide signaling in cells
by: Nile, A., et al.
Published: (2014)

PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling
by: Braccini, L., et al.
Published: (2015)

A sterol-binding protein integrates endosomal lipid metabolism with TOR signaling and nitrogen sensing
by: Mousley, Carl, et al.
Published: (2012)

Nanoparticles Based on Star Polymers as Theranostic Vectors: Endosomal-Triggered Drug Release Combined with MRI Sensitivity
by: Li, Y., et al.
Published: (2015)

Elucidation of the WNT & AKT/Phosphoinositide-3-Kinase Pathways in Colorectal Carcinoma
by: Khor, Tin Oo
Published: (2004)

A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress–induced membrane biogenesis
by: Ren, J., et al.
Published: (2014)

Role of the Lysophosphatidylinositol/GPR55 axis in cancer
by: Falasca, Marco, et al.
Published: (2015)

Emerging role of the KRAS-PDK1 axis in pancreatic cancer
by: Ferro, R., et al.
Published: (2014)

Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase
by: Wood, C., et al.
Published: (2012)

Role of phospholipase C in cell invasion and metastasis
by: Lattanzio, R., et al.
Published: (2013)

Role and regulation of phosphatidylinositol 3-kinase ß in platelet integrin α2ß1 signaling
by: Consonni, A., et al.
Published: (2012)