Evaluation of recurrent glioma and Alzheimer’s disease using novel multimodal brain image processing and analysis

Novel analysis techniques were applied to two different sets of multi-modality brain images. Localised metabolic rate within the hippocampus was assessed for its ability to differentiate between groups of healthy, mildly cognitively impaired, and Alzheimer’s disease brains, and an investigation of i...

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Main Author: Leatherday, Christopher
Format: Thesis
Language:English
Published: Curtin University 2016
Online Access:http://hdl.handle.net/20.500.11937/2238
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author Leatherday, Christopher
author_facet Leatherday, Christopher
author_sort Leatherday, Christopher
building Curtin Institutional Repository
collection Online Access
description Novel analysis techniques were applied to two different sets of multi-modality brain images. Localised metabolic rate within the hippocampus was assessed for its ability to differentiate between groups of healthy, mildly cognitively impaired, and Alzheimer’s disease brains, and an investigation of its potential clinical diagnostic utility was conducted. Relative uptake and retention of two PET tracers (11Carbon Methionine and 18Fluoro Thymidine) in a post-treatment glioma patient cohort was utilized to perform survival prediction analysis.
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spelling curtin-20.500.11937-22382017-02-20T06:37:56Z Evaluation of recurrent glioma and Alzheimer’s disease using novel multimodal brain image processing and analysis Leatherday, Christopher Novel analysis techniques were applied to two different sets of multi-modality brain images. Localised metabolic rate within the hippocampus was assessed for its ability to differentiate between groups of healthy, mildly cognitively impaired, and Alzheimer’s disease brains, and an investigation of its potential clinical diagnostic utility was conducted. Relative uptake and retention of two PET tracers (11Carbon Methionine and 18Fluoro Thymidine) in a post-treatment glioma patient cohort was utilized to perform survival prediction analysis. 2016 Thesis http://hdl.handle.net/20.500.11937/2238 en Curtin University fulltext
spellingShingle Leatherday, Christopher
Evaluation of recurrent glioma and Alzheimer’s disease using novel multimodal brain image processing and analysis
title Evaluation of recurrent glioma and Alzheimer’s disease using novel multimodal brain image processing and analysis
title_full Evaluation of recurrent glioma and Alzheimer’s disease using novel multimodal brain image processing and analysis
title_fullStr Evaluation of recurrent glioma and Alzheimer’s disease using novel multimodal brain image processing and analysis
title_full_unstemmed Evaluation of recurrent glioma and Alzheimer’s disease using novel multimodal brain image processing and analysis
title_short Evaluation of recurrent glioma and Alzheimer’s disease using novel multimodal brain image processing and analysis
title_sort evaluation of recurrent glioma and alzheimer’s disease using novel multimodal brain image processing and analysis
url http://hdl.handle.net/20.500.11937/2238