A robustified modeling approach to analyze pediatric length of stay

PurposeLength of stay (LOS) is an important measure of the cost of pediatric hospitalizations, but the guidelines developed so far are not rigorously evidence-based. This study demonstrates a robust gamma mixed regression approach to analyze the positively skewed LOS variable, which has implications...

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Main Authors: Lee, Andy, Gracey, Michael, Wang, Kui, Yau, K.
Format: Journal Article
Published: Elsevier 2005
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/22296
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author Lee, Andy
Gracey, Michael
Wang, Kui
Yau, K.
author_facet Lee, Andy
Gracey, Michael
Wang, Kui
Yau, K.
author_sort Lee, Andy
building Curtin Institutional Repository
collection Online Access
description PurposeLength of stay (LOS) is an important measure of the cost of pediatric hospitalizations, but the guidelines developed so far are not rigorously evidence-based. This study demonstrates a robust gamma mixed regression approach to analyze the positively skewed LOS variable, which has implications for future studies of pediatric health care management.MethodsThe robustified approach is applied to analyze hospital discharge data on childhood gastroenteritis in Western Australia (n = 514). The model accounts for demographic characteristics and co-morbidities of the patients, as well as the dependency of LOS outcomes nested within the 58 hospitals in the State. The method is compared with the standard linear mixed regression with trimming of extreme observations.ResultsFor the empirical application, the linear mixed regression results are sensitive to the magnitude of trimming. The identified significant factors from the robust regression model, namely infection, failure to thrive, and iron deficiency anemia are resistant to high-LOS outliers.ConclusionsRobust gamma mixed regression appears to be a suitable alternative to analyze the clustered and positively skewed pediatric LOS, without transforming and trimming the data arbitrarily.
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spelling curtin-20.500.11937-222962019-02-19T05:35:00Z A robustified modeling approach to analyze pediatric length of stay Lee, Andy Gracey, Michael Wang, Kui Yau, K. outliers linear mixed model Gastroenteritis transformation robust regression PurposeLength of stay (LOS) is an important measure of the cost of pediatric hospitalizations, but the guidelines developed so far are not rigorously evidence-based. This study demonstrates a robust gamma mixed regression approach to analyze the positively skewed LOS variable, which has implications for future studies of pediatric health care management.MethodsThe robustified approach is applied to analyze hospital discharge data on childhood gastroenteritis in Western Australia (n = 514). The model accounts for demographic characteristics and co-morbidities of the patients, as well as the dependency of LOS outcomes nested within the 58 hospitals in the State. The method is compared with the standard linear mixed regression with trimming of extreme observations.ResultsFor the empirical application, the linear mixed regression results are sensitive to the magnitude of trimming. The identified significant factors from the robust regression model, namely infection, failure to thrive, and iron deficiency anemia are resistant to high-LOS outliers.ConclusionsRobust gamma mixed regression appears to be a suitable alternative to analyze the clustered and positively skewed pediatric LOS, without transforming and trimming the data arbitrarily. 2005 Journal Article http://hdl.handle.net/20.500.11937/22296 10.1016/j.annepidem.2004.10.001 Elsevier fulltext
spellingShingle outliers
linear mixed model
Gastroenteritis
transformation
robust regression
Lee, Andy
Gracey, Michael
Wang, Kui
Yau, K.
A robustified modeling approach to analyze pediatric length of stay
title A robustified modeling approach to analyze pediatric length of stay
title_full A robustified modeling approach to analyze pediatric length of stay
title_fullStr A robustified modeling approach to analyze pediatric length of stay
title_full_unstemmed A robustified modeling approach to analyze pediatric length of stay
title_short A robustified modeling approach to analyze pediatric length of stay
title_sort robustified modeling approach to analyze pediatric length of stay
topic outliers
linear mixed model
Gastroenteritis
transformation
robust regression
url http://hdl.handle.net/20.500.11937/22296