Time Trade-Off Derived EQ-5D Weights for Australia

Background: Cost-utility analyses (CUAs) are increasingly common in Australia. The EuroQol five-dimensional (EQ-5D) questionnaire is one of the most widely used generic preference-based instruments for measuring health-related quality of life for the estimation of quality adjusted life years within...

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Main Authors: Viney, R., Norman, Richard, King, M., Cronin, P., Street, D., Knox, S., Ratcliffe, J.
Format: Journal Article
Published: Wiley-Blackwell Publishing, Inc. 2011
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/22290
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author Viney, R.
Norman, Richard
King, M.
Cronin, P.
Street, D.
Knox, S.
Ratcliffe, J.
author_facet Viney, R.
Norman, Richard
King, M.
Cronin, P.
Street, D.
Knox, S.
Ratcliffe, J.
author_sort Viney, R.
building Curtin Institutional Repository
collection Online Access
description Background: Cost-utility analyses (CUAs) are increasingly common in Australia. The EuroQol five-dimensional (EQ-5D) questionnaire is one of the most widely used generic preference-based instruments for measuring health-related quality of life for the estimation of quality adjusted life years within a CUA. There is evidence that valuations of health states vary across countries, but Australian weights have not previously been developed.Methods: Conventionally, weights are derived by applying the time trade-off elicitation method to a subset of the EQ-5D health states. Using a larger set of directly valued health states than in previous studies, time trade-off valuations were collected from a representative sample of the Australian general population (n = 417). A range of models were estimated and compared as a basis for generating an Australian algorithm.Results: The Australia specific EQ-5D values generated were similar to those previously produced for a range of other countries, but the number of directly valued states allowed inclusion of more interaction effects, which increased the divergence between Australia’s algorithm and other algorithms in the literature.Conclusion: This new algorithm will enable the Australian community values to be reflected in future economic evaluations.
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publishDate 2011
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spelling curtin-20.500.11937-222902017-09-13T13:51:44Z Time Trade-Off Derived EQ-5D Weights for Australia Viney, R. Norman, Richard King, M. Cronin, P. Street, D. Knox, S. Ratcliffe, J. quality-adjusted life years cost-utility analysis EQ-5D outcomes research Background: Cost-utility analyses (CUAs) are increasingly common in Australia. The EuroQol five-dimensional (EQ-5D) questionnaire is one of the most widely used generic preference-based instruments for measuring health-related quality of life for the estimation of quality adjusted life years within a CUA. There is evidence that valuations of health states vary across countries, but Australian weights have not previously been developed.Methods: Conventionally, weights are derived by applying the time trade-off elicitation method to a subset of the EQ-5D health states. Using a larger set of directly valued health states than in previous studies, time trade-off valuations were collected from a representative sample of the Australian general population (n = 417). A range of models were estimated and compared as a basis for generating an Australian algorithm.Results: The Australia specific EQ-5D values generated were similar to those previously produced for a range of other countries, but the number of directly valued states allowed inclusion of more interaction effects, which increased the divergence between Australia’s algorithm and other algorithms in the literature.Conclusion: This new algorithm will enable the Australian community values to be reflected in future economic evaluations. 2011 Journal Article http://hdl.handle.net/20.500.11937/22290 10.1016/j.jval.2011.04.009 Wiley-Blackwell Publishing, Inc. unknown
spellingShingle quality-adjusted life years
cost-utility analysis
EQ-5D
outcomes research
Viney, R.
Norman, Richard
King, M.
Cronin, P.
Street, D.
Knox, S.
Ratcliffe, J.
Time Trade-Off Derived EQ-5D Weights for Australia
title Time Trade-Off Derived EQ-5D Weights for Australia
title_full Time Trade-Off Derived EQ-5D Weights for Australia
title_fullStr Time Trade-Off Derived EQ-5D Weights for Australia
title_full_unstemmed Time Trade-Off Derived EQ-5D Weights for Australia
title_short Time Trade-Off Derived EQ-5D Weights for Australia
title_sort time trade-off derived eq-5d weights for australia
topic quality-adjusted life years
cost-utility analysis
EQ-5D
outcomes research
url http://hdl.handle.net/20.500.11937/22290