Reproductive factors for ovarian cancer in southern Chinese women
Objective: To investigate the association between reproductive factors and the risk of ovarian cancer among southern Chinese women. Methods: A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, between 2006 and 2008. A structured questionnaire was used to obtain infor...
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| Format: | Journal Article |
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Korean Society of Gynecologic Oncology
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/22179 |
| _version_ | 1848750798065893376 |
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| author | Pasalich, Maria Su, Dada Binns, Colin Lee, Andy |
| author_facet | Pasalich, Maria Su, Dada Binns, Colin Lee, Andy |
| author_sort | Pasalich, Maria |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Objective: To investigate the association between reproductive factors and the risk of ovarian cancer among southern Chinese women. Methods: A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, between 2006 and 2008. A structured questionnaire was used to obtain information on parity, oral contraceptive use and other reproductive factors in a sample of 500 incident ovarian cancer patients and 500 controls (mean age, 59 years). Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using unconditional logistic regression models. Results: High parity was inversely associated with ovarian cancer, with an adjusted OR 0.43 (95% CI, 0.30 to 0.62) for women who had given birth to 3 or more children compared to women who had given no more than one birth. Ever use of oral contraceptives was also protective against ovarian cancer; adjusted OR 0.56 (95% CI, 0.40 to 0.78). No association was found for hormone replacement therapy, menopausal status, hysterectomy and family history of ovarian and/or breast cancer. Conclusion: High parity and oral contraceptive use are associated with a lower risk of ovarian cancer in southern Chinese women. |
| first_indexed | 2025-11-14T07:42:33Z |
| format | Journal Article |
| id | curtin-20.500.11937-22179 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:42:33Z |
| publishDate | 2013 |
| publisher | Korean Society of Gynecologic Oncology |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-221792017-09-13T13:51:04Z Reproductive factors for ovarian cancer in southern Chinese women Pasalich, Maria Su, Dada Binns, Colin Lee, Andy Parity Ovarian cancer Oral contraceptives China Objective: To investigate the association between reproductive factors and the risk of ovarian cancer among southern Chinese women. Methods: A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, between 2006 and 2008. A structured questionnaire was used to obtain information on parity, oral contraceptive use and other reproductive factors in a sample of 500 incident ovarian cancer patients and 500 controls (mean age, 59 years). Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using unconditional logistic regression models. Results: High parity was inversely associated with ovarian cancer, with an adjusted OR 0.43 (95% CI, 0.30 to 0.62) for women who had given birth to 3 or more children compared to women who had given no more than one birth. Ever use of oral contraceptives was also protective against ovarian cancer; adjusted OR 0.56 (95% CI, 0.40 to 0.78). No association was found for hormone replacement therapy, menopausal status, hysterectomy and family history of ovarian and/or breast cancer. Conclusion: High parity and oral contraceptive use are associated with a lower risk of ovarian cancer in southern Chinese women. 2013 Journal Article http://hdl.handle.net/20.500.11937/22179 10.3802/jgo.2013.24.2.135 Korean Society of Gynecologic Oncology fulltext |
| spellingShingle | Parity Ovarian cancer Oral contraceptives China Pasalich, Maria Su, Dada Binns, Colin Lee, Andy Reproductive factors for ovarian cancer in southern Chinese women |
| title | Reproductive factors for ovarian cancer in southern Chinese women |
| title_full | Reproductive factors for ovarian cancer in southern Chinese women |
| title_fullStr | Reproductive factors for ovarian cancer in southern Chinese women |
| title_full_unstemmed | Reproductive factors for ovarian cancer in southern Chinese women |
| title_short | Reproductive factors for ovarian cancer in southern Chinese women |
| title_sort | reproductive factors for ovarian cancer in southern chinese women |
| topic | Parity Ovarian cancer Oral contraceptives China |
| url | http://hdl.handle.net/20.500.11937/22179 |