Modelling the time course of antimalarial parasite killing: A tour of animal and human models, translation and challenges

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Modelling the time course of antimalarial parasite killing: A tour of animal and human models, translation and challenges

Malaria remains a global public health concern, and current treatment options are sub-optimal in some clinical settings. For effective chemotherapy, antimalarial drug concentrations must be sufficient to completely remove all of the parasites in the infected host. Optimised dosing therefore requires...

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Bibliographic Details
Main Authors:	Patel, K., Simpson, J., Batty, Kevin, Zaloumis, S., Kirkpatrick, C.
Format:	Journal Article
Published:	Blackwell Publishing 2015
Subjects:	malaria antimalarial chemotherapy pharmacodynamic mechanism based model pharmacokinetics
Online Access:	http://hdl.handle.net/20.500.11937/21926

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