Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products

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Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products

Chemoresistance remains a major problem in the treatment of gastric cancer patients. Hence, novel pharmacological agents that can overcome drug resistance are urgently required. Whether simvastatin can sensitize the gastric cancer to the antitumor effects of capecitabine in vitro and in vivo was inv...

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Bibliographic Details
Main Authors:	Manu, K., Shanmugam, M., Li, F., Chen, L., Siveen, K., Ahn, K., Kumar, Alan Prem, Sethi, G.
Format:	Journal Article
Published:	Springer 2013
Subjects:	Simvastatin Apoptosis Chemoresistance Gastric cancer NF-?B
Online Access:	http://hdl.handle.net/20.500.11937/21839

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