Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules

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Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules

Resistance to chemotherapy represents a major obstacle for long-term remission, and effective strategies toovercome drug resistance would have significant clinical impact. We report that recurrent ovarian carcinomas after paclitaxel/carboplatin treatment have higher levels of spleen tyrosine kinase...

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Bibliographic Details
Main Authors:	Yu, Yu, Gaillard, S., Phillip, J., Huang, T., Pinto, S., Tessarollo, N., Zhang, Z., Pandey, A., Wirtz, D., Ayhan, A., Davidson, B., Wang, T., Shih, I.
Format:	Journal Article
Published:	2015
Online Access:	http://hdl.handle.net/20.500.11937/21755

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