Identification of preferred carbohydrate binding modes in xenoreactive antibodies by combining conformational filters and binding site maps

QR Code

Identification of preferred carbohydrate binding modes in xenoreactive antibodies by combining conformational filters and binding site maps

Carbohydrates are notoriously flexible molecules. However, they have an important role in many biochemical processes as specific ligands. Understanding how carbohydrates are recognized by other biological macromolecules (usually proteins) is therefore of considerable scientific value. Interfering wi...

Full description

Bibliographic Details
Main Authors:	Agostino, Mark, Sandrin, M., Thompson, P., Yuriev, E., Ramsland, Paul
Format:	Journal Article
Published:	Oxford University Press 2010
Online Access:	http://hdl.handle.net/20.500.11937/21546

Similar Items

In silico analysis of antibody-carbohydrate interactions and its application to xenoreactive antibodies
by: Agostino, Mark, et al.
Published: (2009)

Peptide inhibitors of xenoreactive antibodies mimic the interaction profile of the native carbohydrate antigens
by: Agostino, Mark, et al.
Published: (2011)

Docking of carbohydrates into protein binding sites
by: Agostino, Mark, et al.
Published: (2012)

The carbohydrate-binding promiscuity of Euonymus europaeus lectin is predicted to involve a single binding site
by: Agostino, Mark, et al.
Published: (2015)

Reply to 'response to Milland et al.: Carbohydrate residues downstream of the terminal gala(1,3)gal epitope modulate the specificity of xenoreactive antibodies'
by: Milland, J., et al.
Published: (2008)

Antibody-ligand docking: Insights into peptide-carbohydrate mimicry
by: Yuriev, E., et al.
Published: (2008)

Antibody-Carbohydrate Recognition from Docked Ensembles Using the AutoMap Procedure.
by: Dingjan, T., et al.
Published: (2015)

AutoMap: A tool for analyzing protein–ligand recognition using multiple ligand binding modes
by: Agostino, Mark, et al.
Published: (2013)

Carbohydrate-mimetic peptides: structural aspects of mimicry and therapeutic implications
by: Agostino, Mark, et al.
Published: (2011)

Structural biology of carbohydrate xenoantigens
by: Yuriev, E., et al.
Published: (2009)

Antibody Recognition of Cancer-Related Gangliosides and Their Mimics Investigated Using in silico Site Mapping
by: Agostino, Mark, et al.
Published: (2012)

Molecular dynamics simulations of ligand-induced backbone conformational changes in the binding site of the periplasmic lysine-, arginine-, ornithine-binding protein
by: Yang, A., et al.
Published: (2008)

Deprotonation of large calixarenes-cation binding and conformations
by: Harrowfield, J., et al.
Published: (2016)

Carbohydrates in cyberspace
by: Yuriev, E., et al.
Published: (2015)

Molecular docking of carbohydrate ligands to antibodies: Structural validation against crystal structures
by: Agostillo, M., et al.
Published: (2009)

Acquisition of Functional Antibodies That Block the Binding of Erythrocyte-Binding Antigen 175 and Protection Against Plasmodium falciparum Malaria in Children
by: Irani, V., et al.
Published: (2015)

A computational approach for exploring carbohydrate recognition by lectins in innate immunity
by: Agostino, Mark, et al.
Published: (2011)

Structural glycobiology of antibody recognition in xenotransplantation and cancer immunotherapy
by: Agostino, Mark, et al.
Published: (2012)

Structural biology of antibody recognition of carbohydrate epitopes and potential uses for targeted cancer immunotherapies
by: Dingjan, T., et al.
Published: (2014)

Studies on carbohydrate xenoantigens
by: Christiansen, D., et al.
Published: (2012)

From intercalation to groove binding: switching the DNA-binding mode of isostructural transition-metal complexes
by: Ahmad, Haslina, et al.
Published: (2014)

Investigation of the Role of Cell Surface Carbohydrates in Binding and Infection of Group A Human Enteroviruses
by: Diviney, Sinead, et al.
Published: (2009)

Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: conformational analysis and binding mode of multisite inhibitors
by: Di Pietro, Ornella, et al.
Published: (2017)

Helicase binding to DnaI exposes a cryptic DNA-binding site during helicase loading in Bacillus subtilis
by: Ioannou, Charikleia, et al.
Published: (2006)

Gas sorption and binding site studies in metal organic frameworks
by: Eyley, J.E.
Published: (2017)

Prediction of heparin binding sites in bone morphogenetic proteins (BMPs)
by: Gandhi, Neha, et al.
Published: (2012)

Effects of partially dismantling the CD4 binding site glycan fence of HIV-1 envelope glycoprotein trimers on neutralizing antibody induction
by: Crooks, Ema T, et al.
Published: (2017)

Binding connectivity
by: Mohd. Hussain, Mohd. Ramzi, et al.
Published: (2011)

Structural evidence that colicin a protein binds to a novel binding site of TolA protein in Escherichia coli periplasm
by: Li, Chan, et al.
Published: (2012)

Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin
by: Yamasaki, K., et al.
Published: (2017)

Monitoring chemical changes of binding carbohydrates and simulation of temperature profiles during sterilization of oil palm fruit bunches
by: Thang, Yin Mee
Published: (2021)

Characterising the binding interactions and thermodynamics of odour binding protein 3
by: Portman, Katherine Louise
Published: (2012)

Arabidopsis Polycomb Repressive Complex 2 binding sites contain putative GAGA factor binding motifs within coding regions of genes
by: Deng, Weiwei, et al.
Published: (2013)

A possible role for metallic ions in the carbohydrate cluster recognition displayed by a lewis Y specific antibody
by: Farrugia, W., et al.
Published: (2009)

Structural glycobiology: applications in organ transplantation
by: Christiansen, D., et al.
Published: (2012)

Tighter Ligand Binding Can Compensate for Impaired Stability of an RNA-Binding Protein
by: Wallis, C.P., et al.
Published: (2018)

Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein
by: Mittra, Rituparna, et al.
Published: (2017)

Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures
by: Li, Wenlong, et al.
Published: (2017)

CHARACTERIZING THE BINDING SITE OF GPVI INHIBITORS FOR THE DEVELOPMENT OF NOVEL ANTI-PLATELET AGENTS
by: Damaskinaki, Foteini-Nafsika
Published: (2023)

Subdomain IIIA of Dog Albumin Contains a Binding Site Similar to Site II of Human Albumin
by: Kaneko, K., et al.
Published: (2008)

Cannot write session to /tmp/vufind_sessions/sess_f2qc689u0g4fltt91nb8pla068