Stereoselective synthesis towards unnatural proline-based amino acids
A catalytic diastereoselective Mannich reaction promoted by chiral bifunctional urea-type organocatalysts has been developed. Treatment of N-Boc-3-ketoproline with N-Boc-aldimines under mild conditions afforded the corresponding unnatural proline based amino acid derivatives with excellent diastereo...
Full description
Bibliographic Details
| Main Authors: |
Makhathini, S.,
Das, S.,
Singh, T.,
Arvidsson, P.,
Kruger, H.,
Gunosewoyo, Hendra,
Govender, T.,
Naicker, T. |
|---|
| Format: | Journal Article
|
|---|
| Published: |
2016
|
|---|
| Online Access: | http://hdl.handle.net/20.500.11937/21516
|
|---|