Ultra-small fatty acid-stabilized magnetite nanocolloids synthesized by in situ hydrolytic precipitation
© 2015 Kheireddine El-Boubbou et al. Simple, fast, large-scale, and cost-effective preparation of uniform controlled magnetic nanoparticles remains a major hurdle on the way towards magnetically targeted applications at realistic technical conditions. Herein, we present a unique one-pot approach tha...
| Main Authors: | , , , , , , , |
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| Format: | Journal Article |
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Hindawi Publishing Corporation
2015
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| Online Access: | http://hdl.handle.net/20.500.11937/21466 |
| _version_ | 1848750598225133568 |
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| author | El-Boubbou, K. Al-Kaysi, R. Al-Muhanna, M. Bahhari, H. Al-Romaeh, A. Darwish, Nadim Al-Saad, K. Al-Suwaidan, S. |
| author_facet | El-Boubbou, K. Al-Kaysi, R. Al-Muhanna, M. Bahhari, H. Al-Romaeh, A. Darwish, Nadim Al-Saad, K. Al-Suwaidan, S. |
| author_sort | El-Boubbou, K. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | © 2015 Kheireddine El-Boubbou et al. Simple, fast, large-scale, and cost-effective preparation of uniform controlled magnetic nanoparticles remains a major hurdle on the way towards magnetically targeted applications at realistic technical conditions. Herein, we present a unique one-pot approach that relies on simple basic hydrolytic in situ coprecipitation of inexpensive metal salts (Fe<sup>2+</sup> and Fe<sup>3+</sup>) compartmentalized by stabilizing fatty acids and aided by the presence of alkylamines. The synthesis was performed at relatively low temperatures (80°C) without the use of high-boiling point solvents and elevated temperatures. This method allowed for the production of ultra-small, colloidal, and hydrophobically stabilized magnetite metal oxide nanoparticles readily dispersed in organic solvents. The results reveal that the obtained magnetite nanoparticles exhibit narrow size distributions, good monodispersities, high saturation magnetizations, and excellent colloidal stabilities. When the [fatty acid]: [Fe] ratio was varied, control over nanoparticle diameters within the range of 2-10 nm was achieved. The amount of fatty acid and alkylamine used during the reaction proved critical in governing morphology, dispersity, uniformity, and colloidal stability. Upon exchange with water-soluble polymers, the ultra-small sized particles become biologically relevant, with great promise for theranostic applications as imaging and magnetically targeted delivery vehicles. |
| first_indexed | 2025-11-14T07:39:22Z |
| format | Journal Article |
| id | curtin-20.500.11937-21466 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:39:22Z |
| publishDate | 2015 |
| publisher | Hindawi Publishing Corporation |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-214662017-09-13T13:52:23Z Ultra-small fatty acid-stabilized magnetite nanocolloids synthesized by in situ hydrolytic precipitation El-Boubbou, K. Al-Kaysi, R. Al-Muhanna, M. Bahhari, H. Al-Romaeh, A. Darwish, Nadim Al-Saad, K. Al-Suwaidan, S. © 2015 Kheireddine El-Boubbou et al. Simple, fast, large-scale, and cost-effective preparation of uniform controlled magnetic nanoparticles remains a major hurdle on the way towards magnetically targeted applications at realistic technical conditions. Herein, we present a unique one-pot approach that relies on simple basic hydrolytic in situ coprecipitation of inexpensive metal salts (Fe<sup>2+</sup> and Fe<sup>3+</sup>) compartmentalized by stabilizing fatty acids and aided by the presence of alkylamines. The synthesis was performed at relatively low temperatures (80°C) without the use of high-boiling point solvents and elevated temperatures. This method allowed for the production of ultra-small, colloidal, and hydrophobically stabilized magnetite metal oxide nanoparticles readily dispersed in organic solvents. The results reveal that the obtained magnetite nanoparticles exhibit narrow size distributions, good monodispersities, high saturation magnetizations, and excellent colloidal stabilities. When the [fatty acid]: [Fe] ratio was varied, control over nanoparticle diameters within the range of 2-10 nm was achieved. The amount of fatty acid and alkylamine used during the reaction proved critical in governing morphology, dispersity, uniformity, and colloidal stability. Upon exchange with water-soluble polymers, the ultra-small sized particles become biologically relevant, with great promise for theranostic applications as imaging and magnetically targeted delivery vehicles. 2015 Journal Article http://hdl.handle.net/20.500.11937/21466 10.1155/2015/620672 Hindawi Publishing Corporation fulltext |
| spellingShingle | El-Boubbou, K. Al-Kaysi, R. Al-Muhanna, M. Bahhari, H. Al-Romaeh, A. Darwish, Nadim Al-Saad, K. Al-Suwaidan, S. Ultra-small fatty acid-stabilized magnetite nanocolloids synthesized by in situ hydrolytic precipitation |
| title | Ultra-small fatty acid-stabilized magnetite nanocolloids synthesized by in situ hydrolytic precipitation |
| title_full | Ultra-small fatty acid-stabilized magnetite nanocolloids synthesized by in situ hydrolytic precipitation |
| title_fullStr | Ultra-small fatty acid-stabilized magnetite nanocolloids synthesized by in situ hydrolytic precipitation |
| title_full_unstemmed | Ultra-small fatty acid-stabilized magnetite nanocolloids synthesized by in situ hydrolytic precipitation |
| title_short | Ultra-small fatty acid-stabilized magnetite nanocolloids synthesized by in situ hydrolytic precipitation |
| title_sort | ultra-small fatty acid-stabilized magnetite nanocolloids synthesized by in situ hydrolytic precipitation |
| url | http://hdl.handle.net/20.500.11937/21466 |