Optimal control of diabetes

This thesis considers optimal control problems related to one of the major global health problems, Diabetes. We adopt a comprehensive dynamic model of the blood glucose regulatory system and show how it can be readily fitted to individuals. Based on this, we develop a composite dynamic model for sim...

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Bibliographic Details
Main Author: Al Helal, Zahra Hassan A
Format: Thesis
Language:English
Published: Curtin University 2016
Online Access:http://hdl.handle.net/20.500.11937/2107
Description
Summary:This thesis considers optimal control problems related to one of the major global health problems, Diabetes. We adopt a comprehensive dynamic model of the blood glucose regulatory system and show how it can be readily fitted to individuals. Based on this, we develop a composite dynamic model for simulating the effects of exercise and subcutaneous insulin injections on the blood glucose regulatory system. We then determine that optimal treatment regimens on the basis of the composite model.