HBV-related hepatocellular carcinoma: The role of integration, viral proteins and miRNA
The development of hepatocellular carcinoma during chronic hepatitis B infection is a multifactorial process thought to be a consequence of several direct and indirect mechanisms. In this review we discuss how viral proteins and cycles of ongoing liver damage and regeneration, coupled with HBV DNA i...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
2012
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| Online Access: | http://hdl.handle.net/20.500.11937/20581 |
| _version_ | 1848750345758441472 |
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| author | Lim, L. Tran, B. Vincan, Elizabeth Locarnini, S. Warner, N. |
| author_facet | Lim, L. Tran, B. Vincan, Elizabeth Locarnini, S. Warner, N. |
| author_sort | Lim, L. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | The development of hepatocellular carcinoma during chronic hepatitis B infection is a multifactorial process thought to be a consequence of several direct and indirect mechanisms. In this review we discuss how viral proteins and cycles of ongoing liver damage and regeneration, coupled with HBV DNA integration and aberrant miRNA expression may enhance the risk for the development of hepatocellular carcinoma. © 2012 Future Medicine Ltd. |
| first_indexed | 2025-11-14T07:35:22Z |
| format | Journal Article |
| id | curtin-20.500.11937-20581 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T07:35:22Z |
| publishDate | 2012 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-205812017-09-13T13:49:37Z HBV-related hepatocellular carcinoma: The role of integration, viral proteins and miRNA Lim, L. Tran, B. Vincan, Elizabeth Locarnini, S. Warner, N. The development of hepatocellular carcinoma during chronic hepatitis B infection is a multifactorial process thought to be a consequence of several direct and indirect mechanisms. In this review we discuss how viral proteins and cycles of ongoing liver damage and regeneration, coupled with HBV DNA integration and aberrant miRNA expression may enhance the risk for the development of hepatocellular carcinoma. © 2012 Future Medicine Ltd. 2012 Journal Article http://hdl.handle.net/20.500.11937/20581 10.2217/fvl.12.113 restricted |
| spellingShingle | Lim, L. Tran, B. Vincan, Elizabeth Locarnini, S. Warner, N. HBV-related hepatocellular carcinoma: The role of integration, viral proteins and miRNA |
| title | HBV-related hepatocellular carcinoma: The role of integration, viral proteins and miRNA |
| title_full | HBV-related hepatocellular carcinoma: The role of integration, viral proteins and miRNA |
| title_fullStr | HBV-related hepatocellular carcinoma: The role of integration, viral proteins and miRNA |
| title_full_unstemmed | HBV-related hepatocellular carcinoma: The role of integration, viral proteins and miRNA |
| title_short | HBV-related hepatocellular carcinoma: The role of integration, viral proteins and miRNA |
| title_sort | hbv-related hepatocellular carcinoma: the role of integration, viral proteins and mirna |
| url | http://hdl.handle.net/20.500.11937/20581 |